Optimization of supercritical fluid extraction of dl-tetrahydropalmatine from rhizome of Corydalis yanhusuo W.T. Wang with orthogonal array design

Liu, Ben; Shen, Bo; Guo, Feng; Chang, Yiling

doi:10.1016/j.seppur.2008.10.003

Cited by 25 publications

(15 citation statements)

References 24 publications

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“…The orthogonal method is generally used to optimise the extraction method (Liu et al , 2008). However, with an increase in experimental factors, orthogonal array design has not been applied in the experiment.…”

Section: Introductionmentioning

confidence: 99%

Application of response surface methodology to optimise supercritical carbon dioxide extraction of oil from rapeseed (Brassica napusL.)

Wang

Liu

et al. 2012

Int J of Food Sci Tech

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Summary Supercritical CO2 fluid extraction technology was used to extract oil from rapeseed. Extraction temperature, pressure, time and the sample particle size were selected and optimised by response surface methodology. Conventional solvent extraction was applied as a comparative method. The maximum extraction yield of 32.65 ± 1.01% was achieved at a temperature of 40 °C and a pressure of 345 bar, using an extraction time of 3 h and a 60‐mesh particle size. The chemical compositions of rapeseed oil using esterification method were investigated by GC–MS. The result indicates that the main fatty acids are palmitic acid (2.60%), oleic acid (16.54%), linoleic acid (9.62%), linolenic acid (4.77%), eicosenoic acid (11.20%) and erucic acid (47.09%), respectively. Supercritical fluid extraction has been proved to be an effective technique for extracting oil from Brassica napus L.

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Section: Introductionmentioning

confidence: 99%

Application of response surface methodology to optimise supercritical carbon dioxide extraction of oil from rapeseed (Brassica napusL.)

Wang

Liu

et al. 2012

Int J of Food Sci Tech

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“…The product is decaffeinated coffee and tea [378]. There are also some other alkaloids with health-beneficial properties, such as boldine [208], sinomenine [380], indole [381,382], purine [383], tetrahydropalmatine [384], nicotine [385], isoquinolines [386], etc. [387] investigated safranol extraction with supercritical CO 2 .…”

Section: Alkaloids and Other Bioactive Phytochemicalsmentioning

confidence: 99%

Application of supercritical fluid extraction for separation of nutraceuticals and other phytochemicals from plant material

Oman

Škerget

Knez

2013

Maced. J. Chem. Chem. Eng.

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In present work a literature review of application of supercritical fluid extraction (SFE) for isolation of nutraceuticals and some other phytochemicals up to December of 2012 is presented. Manuscript provides knowledge of SFE processes and possible aplications of SFE for extraction of bioactive compounds which serve as nutraceuticals. Compounds are classified into groups based on their chemical nature (carotenoids, flavonoids and other phenolic compounds, essential oils, lipids and fatty acids, and alkaloids and other bioactive phytochemicals) and they are reviewed in tabular form along with plant material, from which they were extracted using supercritical fluids.

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“…In this sense, supercritical fluid extraction is safer for the human being, due to the reduction of the volume of organic solvent and extraction time [16]. Authors have been extracting alkaloids semipurified by supercritical fluid extraction [17–19], and we have extracted the pyrrolidine alkaloids with better yield than chloroform [12]. Considering the important biological activities of compound 1 , it is indispensable to evaluate the factors which influence its extraction using supercritical carbon dioxide.…”

Section: Introductionmentioning

confidence: 99%

Supercritical Fluid Extraction of Pyrrolidine Alkaloid from Leaves of Piper amalago L.

Carrara

Filho

Garcia

et al. 2017

Evidence-Based Complementary and Alternative Medicine

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Supercritical fluid extraction was used to extract the alkaloid N-[7-(3′,4′-methylenedioxyphenyl)-2(Z),4(Z)-heptadienoyl]pyrrolidine from leaves of Piper amalago L. A three-level orthogonal array design matrix, OAD OA9(34), was used for optimization of the parameters of supercritical extraction of the alkaloid, employing supercritical carbon dioxide: extraction time (20, 40, and 60 min), temperature (40, 50, and 60°C), pressure (150, 200, and 250 bar), and the use of cosolvents (ethanol, methanol, and propyleneglycol). All parameters had significant effect on the alkaloid yield. The alkaloid yield after 60 min of extraction without cosolvents at 9 different conditions (32) in terms of temperature (40, 50, and 60°C) and pressure (150, 200, and 250 bar) was also evaluated. The optimal yield (≈3.8 mg g−1) was obtained with supercritical CO2 + methanol (5% v : v) at 40°C and 200 bar for 60 min of extraction.

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Optimization of supercritical fluid extraction of dl-tetrahydropalmatine from rhizome of Corydalis yanhusuo W.T. Wang with orthogonal array design

Cited by 25 publications

References 24 publications

Application of response surface methodology to optimise supercritical carbon dioxide extraction of oil from rapeseed (Brassica napusL.)

Application of response surface methodology to optimise supercritical carbon dioxide extraction of oil from rapeseed (Brassica napusL.)

Application of supercritical fluid extraction for separation of nutraceuticals and other phytochemicals from plant material

Supercritical Fluid Extraction of Pyrrolidine Alkaloid from Leaves of Piper amalago L.

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