Optimization of Solvent Extraction of the Leaves of Premna serratifolia and Quantitation of Premnaodoroside A by Validated TLC-densitometric Method

Yee, Khin Su; Sukwattanasinit, Tasamaporn; Sotanaphun, Uthai; Wetwitayaklung, Penpun; Wangwattana, Bunyapa; Narakornwit, Worrakanya

doi:10.5530/pj.2021.13.213

2021

DOI: 10.5530/pj.2021.13.213

|View full text |Cite

Optimization of Solvent Extraction of the Leaves of Premna serratifolia and Quantitation of Premnaodoroside A by Validated TLC-densitometric Method

Khin Su Yee¹,

Tasamaporn Sukwattanasinit²,

Uthai Sotanaphun³

et al.

Abstract: The leaves of P. serratifolia L. were collected from three sources, (1) Aungmyethazan, (2) Chanayethazan and (3) Pathingyi, Mandalay, Myanmar, in December, 2018. Identification of

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2022

Publication Types

Select...

Article2

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

(1 citation statement)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The flowers are small. It mostly grows in sandy soil and scrubs jungles along seacoasts and mangrove forests 6 .…”

mentioning

confidence: 99%

Phytochemistry and Pharmacological Potentials of Premna serratifolia L.: Traditional Medicinal Plant Used by Local People in Kalimantan

Khairunnisa

Febriyanti²,

Muhaimin³

2022

ijbp

View full text Add to dashboard Cite

Millions of people worldwide have been using herbal medicines for thousands of years, due to their great interest in traditional medicines. One of the plants in Indonesia which has medicinal properties but is not widely known by the public and used is Bebuas plant. Bebuas (Premna serratifolia Linn) has been observed growing in West Kalimantan. The people of West Kalimantan used bebuas leaves to reduce cholesterol levels, the young leaves used as a traditional medicine to expel wind in the body quickly, treat intestinal worms, and increase breast milk for nursing mothers, and the decoction of fresh leaves is used for colds and fever medicine. Several studies report bebuas (Premna serratifolia L.) had many pharmacological activities. Bebuas contains flavonoids, saponins, tannins and triterpenoids/steroids that have a role in pharmacological activity. The present review aims to summarize the current state of scientific evidence on the pharmacological potentials of P. serratifolia. The subject of literature published from 2012 to 2022 were obtained frominternational research databases including PubMed, Google Scholar, EBSCO, SCOPUS, and Cochrane, using the keywords Premna serratifolia L., traditional medicine, medicinal plants, and pharmacology. The pharmacological activities which are discussed further in the review including antioxidant, anti-arthritic, anticholesterol, anti-inflammatory, antimicrobial, antihelmintic, antidiabetic, and anticancer/cytotoxic. The study suggests that Premna serratifolia L. is a potent source for further development of phytomedicine.

show abstract

“…The flowers are small. It mostly grows in sandy soil and scrubs jungles along seacoasts and mangrove forests 6 .…”

mentioning

confidence: 99%

Phytochemistry and Pharmacological Potentials of Premna serratifolia L.: Traditional Medicinal Plant Used by Local People in Kalimantan

Khairunnisa

Febriyanti²,

Muhaimin³

2022

ijbp

View full text Add to dashboard Cite

show abstract

Chemical and Pharmacological Properties of Selected Medicinal Plant Species From Genus Premna and Their Immunomodulatory Potentials

BELINDA

FEBRIYANTI²,

MUHAIMIN³

2022

Int J App Pharm

View full text Add to dashboard Cite

Epidemiological data today show an increase in immune diseases; hence increasing awareness to maintain and increase the body's immunity is essential. Immunomodulators are substances that improve the human immune system by stimulating, inhibiting, or regulating components in the immune system. Plants produce secondary metabolites which provide beneficial effects on human health, including immunomodulatory properties. Natural immunomodulators can be used to minimize side effects and toxicity compared to synthetic materials because using synthetic immunomodulators may result undesirable side effects, such as pulmonary toxicity, myelosuppression, alopecia, and nephrotoxicity. Besides that, using plants as medicine is safer to use, more effective against a wide spectrum of pathogens, and relatively cheaper than synthetic medicine. Some of the medicinal plants which have immunomodulatory properties belong to the genus Premna from Lamiaceae. Alkaloids, flavonoids, phenolics, saponins, terpenoids, polysaccharides, and fatty acids supported the pharmacological effect of Premna sp. as immunomodulatory agent. The present work reviews some species in genus Premna, which were the subject of literature search based on major scientific databases, including PubMed, Elsevier, SpringerLink, Science Direct, Scopus, Mendeley, and Google Scholar. This review presents a series of selected plants from genus Premna sp. including their chemical and pharmacological properties as well as immunomodulatory potential.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Optimization of Solvent Extraction of the Leaves of Premna serratifolia and Quantitation of Premnaodoroside A by Validated TLC-densitometric Method

Abstract: The leaves of P. serratifolia L. were collected from three sources, (1) Aungmyethazan, (2) Chanayethazan and (3) Pathingyi, Mandalay, Myanmar, in December, 2018. Identification of

Cited by 2 publications

References 12 publications

Phytochemistry and Pharmacological Potentials of Premna serratifolia L.: Traditional Medicinal Plant Used by Local People in Kalimantan

Phytochemistry and Pharmacological Potentials of Premna serratifolia L.: Traditional Medicinal Plant Used by Local People in Kalimantan

Chemical and Pharmacological Properties of Selected Medicinal Plant Species From Genus Premna and Their Immunomodulatory Potentials

Contact Info

Product

Resources

About