Quantum computing (QC) is founded on the principles of quantum entanglement and the superposition of matter. It employs advanced computation techniques rather than conventional ones. To circumvent the limitations of conventional computing, new supercomputers employ quantum mechanics knowledge, which allows for the coherence of ones and zeros. Several fields like finance, healthcare, cybersecurity, transportation, climate change, and many more are taking advantage of QC. Indoor environmental quality (IEQ) is also one of the sectors that can benefit enormously with QC. The IEQ contains several parameters. Major IEQ parameters are indoor air quality, thermal comfort, acoustic comfort, and visual comfort. These parameters are associated with several physical, chemical, and biological components, which need critical computational considerations for accurate results and better understanding as the data can be highly overlapped. This chapter contains possible forthcoming research opportunities available in the collaborative work between “indoor environment” and “quantum computing.”