Optimization of process variables for supercritical fluid extraction of ergothioneine and polyphenols from Pleurotus ostreatus and correlation to free-radical scavenging activity

Bhattacharya, Mrittika; Srivastav, P.P.; Mishra, Hari Niwas

doi:10.1016/j.supflu.2014.07.031

Cited by 28 publications

(17 citation statements)

References 31 publications

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“…Bhattacharya et al [75] also demonstrated that pressure and the amount of cosolvent were the most effective parameters on their system response, and that the optimal conditions to obtain the highest ergothioneine and polyphenols concentration from Pleurotus ostreatus along with the highest antioxidant capacity were 210 bar, 48 °C with an ethanol amount of 133 ml.…”

Section: Operative Conditionsmentioning

confidence: 99%

Supercritical fluid extraction of bioactive compounds

Silva

Rocha-Santos

Duarte

2016

TrAC Trends in Analytical Chemistry

498

219

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An ideal extraction method should be swift, yield quantitative recovery without degradation, and the extracts should be easily separated from the solvent. The development and application of alternative green technology to replace conventional extraction methods with improved extraction efficiency and low environmental impact for the determination of natural bioactive compounds is therefore, highly important. Supercritical fluid technology offers features that overcome many limitations of conventional extraction methods. This review presents an analytical overview regarding the application of supercritical fluids in the extraction of bioactive compounds and their operative extraction conditions, along with the investigation of further improvements on the extraction efficiency and the applied techniques for the structural characterization and identification of such bioactive compounds.

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Section: Operative Conditionsmentioning

confidence: 99%

Supercritical fluid extraction of bioactive compounds

Silva

Rocha-Santos

Duarte

2016

TrAC Trends in Analytical Chemistry

498

219

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“…6 shows that there was a decrease in the content of polyphenol from 85.2 to 57 mg gallic acid equivalent per g of spent tea. Extraction at lower pressures (15, 25 MPa) resulted in reduced loss of polyphenols (Bhattacharya et al, 2014). Flavonoids are also an important active biological group present in fresh tea leaves.…”

Section: Solubility Of Caffeine In Supercritical Co 2 +Etohmentioning

confidence: 99%

Mass transfer and kinetic modelling of supercritical CO 2 extraction of fresh tea leaves (Camellia sinensis L.)

Gadkari

Manohar

2017

Braz. J. Chem. Eng.

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-Supercritical carbon dioxide extraction was employed to extract solids from fresh tea leaves (Camellia sinensis L.) at various pressures(15 to 35 MPa) and temperatures (313 to 333K) with addition of ethanol as a polarity modifier. The diffusion model and Langmuir model fit well to experimental data and the correlation coefficients were greater than 0.94. Caffeine solubility was determined in supercritical CO 2 and the Gordillo model was employed to correlate the experimental solubility values. The Gordillo model fit well to the experimental values with a correlation coefficient 0.91 and 8.91% average absolute relative deviation. Total phenol content of spent materials varied from 57 to 85.2 mg of gallic acid equivalent per g spent material, total flavonoid content varied from 50.4 to 58.2 mg of rutin equivalent per g spent material and the IC50 value (antioxidant content) varied from 27.20 to 38.11 µg of extract per mL. There was significant reduction in polyphenol, flavonoid and antioxidant content in the extract when supercritical CO 2 extraction was carried out at a higher pressure of 35 MPa.

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“…After the system had reached the required temperature and pressure, ethanol was pumped from the co‐solvent pump (model 1500, Applied Separations; capacity 0.000–9.999 mL min −1 ) simultaneously with scCO 2 through the feed. The volume of ethanol utilized was divided by the total extraction time to calculate the flow rate of co‐solvent . Cholesterol extracts were collected in glass vials, and the ethanol from the residual samples was evaporated under vacuum.…”

Section: Methodsmentioning

confidence: 99%

“…36 Based on the extraction parameters used, extraction vessel size and available literature, the static and dynamic times of the process were maintained at 10 and 80 min, respectively. 37,38 After the system had reached the required temperature and pressure, ethanol was pumped from the co-solvent pump (model 1500, Applied Separations; capacity 0.000-9.999 mL min −1 ) simultaneously with scCO 2 through the feed. The volume of ethanol utilized was divided by the total extraction time to calculate the flow rate of co-solvent.…”

Section: Supercritical Fluid Extraction Of Cholesterolmentioning

confidence: 99%