Optimization of phenolic compound recovery and antioxidant activity of light and dark dried fig (Ficus carica L.) varieties

Bachir‐bey, Mostapha; Louailèche, Hayette; Zemouri, Salima

doi:10.1007/s10068-013-0258-7

Cited by 35 publications

(21 citation statements)

References 23 publications

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“…Two important and effective phenomena in ultrasound are the effect of cavitation and temperature. Cavitation is affected by the bursting of bubbles and heat by swelling and destruction of the cellular structure, thereby increasing the mass transfer of intracellular material to the solvent [51]. In this study, at the beginning of the extraction process at lower temperatures, the effect of heat was negligible, and as a result, the extraction performance was lower.…”

Section: Antioxidant Activity (Ic50)mentioning

confidence: 72%

Optimization of Aqueous Extraction Conditions of Inulin from the Arctium lappa L. Roots Using Ultrasonic Irradiation Frequency

Esmaeili

Hashemiravan

Eshaghi

et al. 2021

Journal of Food Quality

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Ultrasound-assisted extraction is a promising technique to obtain active compounds from plants with high efficiency. The present study was conducted in two sections. In the first phase, the effect of solvent type (methanol, ethanol, water, and water-ethanol (50 : 50, v/v)) on inulin extraction yield from burdock roots (Arctium lappa L.) was investigated by the conventional method. The second phase aim was to optimize the condition of inulin and phenolic compounds including sonication time (10–40 min), sonication temperature (40–70°C), and solid/solvent ratio (1 : 20–1:40 g/ml) using response surface methodology (RSM). The results demonstrated that the highest inulin efficiency was extracted by water in the conventional method, which is equal to 10.32%. The optimum conditions of ultrasound-assisted water extraction for independent variables including sonication time and temperature as well as solid/water ratio were 36.65 min, 55.48°C, and 1 : 35 g/ml, respectively, which were determined on the maximization of inulin and total phenol content and minimization of IC50. At this optimum condition, inulin yield, phenolic compounds, and IC50 were found to be 12.46%, 18.85 mg GA/g DW, and 549.85 µg/ml, respectively. Regarding the results of this research, ultrasound-assisted extraction can be used as an alternative to the conventional extraction methods in extracting bioactive compounds from medicinal plants because it may improve the mass transfer, reducing the extraction time and the solvent used.

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Section: Antioxidant Activity (Ic50)mentioning

confidence: 72%

Optimization of Aqueous Extraction Conditions of Inulin from the Arctium lappa L. Roots Using Ultrasonic Irradiation Frequency

Esmaeili

Hashemiravan

Eshaghi

et al. 2021

Journal of Food Quality

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“…F carica is estimated to contain a total phenol of 17.8 to 815 mg/100 g in leaves, and 3241.2 to 3447.36 mg/100 g in fruits. [16][17][18][19] Similarly, the results of this indicate that F carica leaf and fruit extracts contained several antioxidants, such as flavonoid and tannin. The presence of flavonoid, tannin, and other polyphenolic compounds can counteract free radicals by donating protons to free radicals and therefore terminate potentially damaging chain reactions.…”

Section: Discussionmentioning

confidence: 91%

Anticancer Activity of Methanol Extract of Ficus carica Leaves and Fruits Against Proliferation, Apoptosis, and Necrosis in Huh7it Cells

et al. 2019

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The polyphenol plant extracts have previously been demonstrated to act as chemopreventive and anticancer agents. Ficus carica is a rich source of polyphenols, yet its antioxidant and anticancer activities remain poorly characterized. This study aimed to determine the anticancer activity of F carica leaf and fruit extracts by investigating their impact on proliferation, apoptosis, and Huh7it cell necrosis. Leaves and fruits were extracted using methanol, and the phytochemical contents were analyzed using Fourier-transform infrared spectroscopy. The antioxidant activity was measured using the 2,2-diphenyl-1-picrylhydrazyl method. Anticancer activities were examined through MTT (3-(4,5-dimethylthiazol-2yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium) assay on Huh7it liver cancer cells. The apoptosis and necrosis conditions were examined using Annexin biomarkers V-PI and later analyzed in flow cytometry. F carica leaves and fruit examined were found to have strong antioxidant activities with IC 50 values of 7.9875 µg/mL and 13.402 µg/mL, respectively. MTT assay results indicated F carica leaves and fruit had IC 50 values >653 μg/mL and >2000 μg/mL, respectively. The flow cytometry analysis indicated a higher percentage of Huh7it apoptosis and necrosis in leaf extracts compared with fruit extracts. The difference in anticancer activity was attributed to differing compounds present in each extract.

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“…The capacity of the samples to scavenge the DPPH‐free radicals was measured using a previously ascribed technique (Bey, Louaileche, & Zemouri, ). In this context, 500 μl of each sample was charged with 500 μl of ethanol (99.5%) and 25 μl of DPPH (0.22%) in ethanol (99.5%), then vigorously mixed, and then was stored for 30 min at a dark place.…”

Section: Methodsmentioning

confidence: 99%

The effects of hydrolysis condition on antioxidant activity of protein hydrolyzate from quinoa

Mahdavi-Yekta

Nouri

Azizi

2019

Food Science & Nutrition

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In the present study, quinoa protein hydrolyzate was prepared using alcalase and pepsin enzymes. Then, the effect of different temperatures (40, 45, 50, and 55°C), periods of time (60, 120, 150, 180, and 210 min), and the ratio of enzyme to substrate (30, 60, and 90 Anson unit/kg protein) on degree of hydrolysis were examined. Also, the antioxidant activity was assessed using DPPH radical scavenging test, and investigated using a completely randomized design. According to results, the optimum condition to produce hydrolyzates with the highest degree of hydrolysis (24.65%) was 55°C, 210 min, with ratio of enzyme to substrate of 60 Anson unit/kg protein, The highest antioxidant activity (35.44) of protein hydrolyzed was achieved at 150 min, 50°C, and the ratio of enzyme to substrate 60 (Anson unit/kg protein). Moreover, there was no significant ( p > 0.05) between the level of hydrolysis and the antioxidant activity was among different time and temperatures. In conclusion, the peptide derived from quinoa protein showed a sufficient antioxidant activity to be incorporated in food products.

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Optimization of phenolic compound recovery and antioxidant activity of light and dark dried fig (Ficus carica L.) varieties

Cited by 35 publications

References 23 publications

Optimization of Aqueous Extraction Conditions of Inulin from the Arctium lappa L. Roots Using Ultrasonic Irradiation Frequency

Optimization of Aqueous Extraction Conditions of Inulin from the Arctium lappa L. Roots Using Ultrasonic Irradiation Frequency

Anticancer Activity of Methanol Extract of Ficus carica Leaves and Fruits Against Proliferation, Apoptosis, and Necrosis in Huh7it Cells

The effects of hydrolysis condition on antioxidant activity of protein hydrolyzate from quinoa

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