Optimization of myocardial nulling in pediatric cardiac MRI

Tham, Edythe B; Hung, Ryan; Myers, K.; Crawley, Cinzia; Noga, Michelle

doi:10.1007/s00247-011-2276-z

Cited by 3 publications

(3 citation statements)

References 25 publications

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“…In LGE CMR, an inversion recovery sequence is usually employed to differentiate hyperintensity of infarcted tissue from the adjacent hypo-intensity of normal tissue ( 22 23 ). Inversion time is adjusted to null normal myocardial signals ( 24 ).…”

Section: Discussionmentioning

confidence: 99%

Self-Gated Late Gadolinium Enhancement at 7T to Image Rats with Reperfused Acute Myocardial Infarction

et al. 2018

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ObjectiveA failed electrocardiography (ECG)-trigger often leads to a long acquisition time (TA) and deterioration in image quality. The purpose of this study was to evaluate and optimize the technique of self-gated (SG) cardiovascular magnetic resonance (CMR) for cardiac late gadolinium enhancement (LGE) imaging of rats with myocardial infarction/reperfusion.Materials and MethodsCardiovascular magnetic resonance images of 10 rats were obtained using SG-LGE or ECG with respiration double-gating (ECG-RESP-gating) method at 7T to compare differences in image interference and TA between the two methods. A variety of flip angles (FA: 10°–80°) and the number of repetitions (NR: 40, 80, 150, and 300) were investigated to determine optimal scan parameters of SG-LGE technique based on image quality score and contrast-to-noise ratio (CNR).ResultsSelf-gated late gadolinium enhancement allowed successful scan in 10 (100%) rats. However, only 4 (40%) rats were successfully scanned with the ECG-RESP-gating method. TAs with SG-LGE varied depending on NR used (TA: 41, 82, 154, and 307 seconds, corresponding to NR of 40, 80, 150, and 300, respectively). For the ECG-RESP-gating method, the average TA was 220 seconds. For SG-LGE images, CNR (42.5 ± 5.5, 43.5 ± 7.5, 54 ± 9, 59.5 ± 8.5, 56 ± 13, 54 ± 8, and 41 ± 9) and image quality score (1.85 ± 0.75, 2.20 ± 0.83, 2.85 ± 0.37, 3.85 ± 0.52, 2.8 ± 0.51, 2.45 ± 0.76, and 1.95 ± 0.60) were achieved with different FAs (10°, 15°, 20°, 25°, 30°, 35°, and 40°, respectively). Optimal FAs of 20°–30° and NR of 80 were recommended.ConclusionSelf-gated technique can improve image quality of LGE without irregular ECG or respiration gating. Therefore, SG-LGE can be used an alternative method of ECG-RESP-gating.

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Section: Discussionmentioning

confidence: 99%

Self-Gated Late Gadolinium Enhancement at 7T to Image Rats with Reperfused Acute Myocardial Infarction

et al. 2018

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“…Volumetric analyses and early and late gadolinium enhancement imaging were acquired, using free-breathing techniques that were optimised for infant imaging. 1 The MRI showed no areas of late gadolinium enhancement to suggest fibrosis, infarct, or inflammation. Biventricular function was normal, with mild enlargement of the right ventricle.…”

Section: Casementioning

confidence: 95%

“…The MRI was performed on a Siemens Aera 1.5T scanner (Siemens Healthcare, Erlangen, Germany) with a feed-and-bundle technique using infant immobiliser; therefore, sedation was not required. Volumetric analyses and early and late gadolinium enhancement imaging were acquired, using free-breathing techniques that were optimised for infant imaging 1 …”

Section: Casementioning

confidence: 99%

Ductal constriction during dexamethasone treatment in an anti-SSA-antibody-exposed fetus with signs of myocardial inflammation

2016

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This report describes the clinical course and multi-modality imaging findings in an anti-SSA-antibody-exposed fetus with suspected myocardial inflammation. Postnatal cardiac MRI - using fast acquisition, free-breathing with feed-and-swaddle technique - was used to evaluate for myocardial fibrosis/inflammation. This is the first published report, to our knowledge, of ductal constriction temporally associated with oral dexamethasone therapy in an anti-SSA-antibody-exposed fetus and of the use of this unique postnatal MRI protocol in this setting.

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The International Society for Heart and Lung Transplantation Guidelines for the management of pediatric heart failure: Executive summary

Kirk

Dipchand

Rosenthal

et al. 2014

The Journal of Heart and Lung Transplantation

254

212

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Optimization of myocardial nulling in pediatric cardiac MRI

Cited by 3 publications

References 25 publications

Self-Gated Late Gadolinium Enhancement at 7T to Image Rats with Reperfused Acute Myocardial Infarction

Self-Gated Late Gadolinium Enhancement at 7T to Image Rats with Reperfused Acute Myocardial Infarction

Ductal constriction during dexamethasone treatment in an anti-SSA-antibody-exposed fetus with signs of myocardial inflammation

The International Society for Heart and Lung Transplantation Guidelines for the management of pediatric heart failure: Executive summary

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