Optimization of MLVA loci combination using metaheuristic methods
Grace Yee Lin Ng,
Kim Loon Ang,
Shing Chiang Tan
et al.
Abstract:Multilocus variable number tandem repeat analysis (MLVA) utilizes short DNA repeat polymorphism in genomes, which is termed variable number tandem repeat (VNTR), to differentiate closely related organisms. One research challenge is to find an optimal set of VNTR to distinguish different members accurately. An intuitive method is to use an exhaustive search method. However, this method is not an efficient way to find optimal solutions from a dataset comprising many attributes (loci) due to the curse of dimensio… Show more
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