Optimization of microwave-assisted extraction recovery of bioactive compounds from Origanum glandulosum and Thymus fontanesii

Nabet, Nacim; Gilbert-López, Bienvenida; Madani, Khodir; Herrero, Miguel; Ibáñez, Elena; Mendiola, J. A.

doi:10.1016/j.indcrop.2018.12.032

Cited by 50 publications

(31 citation statements)

References 43 publications

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“…Similarly, more flavone diversity was observed in the extract of roots from Salvia viridis obtained from UAE and MAE than from SFE [144]. For Origanum species, O. glandulosum (leaves and flowers) and O. majorana (leaves) have been extracted by MAE and UAE, respectively, with apigenin and luteolin derivatives in the former, but only luteolin derivatives in the latter [61,147]. However, in O. vulgare aerial parts, the same flavones profile was found using UAE, PLE, and MAE [148], while fewer flavones were found in another extract obtained by PLE [60,149].…”

Section: Alternative Methods (Environmentally Friendly)mentioning

confidence: 89%

Extraction Processes Affect the Composition and Bioavailability of Flavones from Lamiaceae Plants: A Comprehensive Review

et al. 2021

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Lamiaceae plants are a widespread family of herbaceous plants with around 245 plant genera and nearly 22,576 species distributed in the world. Some of the most representative and widely studied Lamiaceae plants belong to the Ocimum, Origanum, Salvia, and Thymus genera. These plants are a rich source of bioactive molecules such as terpenes, flavonoids, and phenolic acids. In this sense, there is a subgroup of flavonoids classified as flavones. Flavones have antioxidant, anti-inflammatory, anti-cancer, and anti-diabetic potential; thus, efficient extraction techniques from their original plant matrixes have been developed. Currently, conventional extraction methods involving organic solvents are no longer recommended due to their environmental consequences, and new environmentally friendly techniques have been developed. Moreover, once extracted, the bioactivity of flavones is highly linked to their bioavailability, which is often neglected. This review aims to comprehensively gather recent information (2011–2021) regarding extraction techniques and their important relationship with the bioavailability of flavones from Lamiaceae plants including Salvia, Ocimum, Thymus, and Origanum.

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Section: Alternative Methods (Environmentally Friendly)mentioning

confidence: 89%

Extraction Processes Affect the Composition and Bioavailability of Flavones from Lamiaceae Plants: A Comprehensive Review

et al. 2021

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“…Improving the yield of active ingredients by optimizing the processing methods is a good way to achieve the above goals ( Mishra et al, 2020 ; Nabet et al, 2019 ; Wang et al, 2018a ). Typically, the active ingredients in medicinal plants are secondary metabolites that are closely related to cultivation methods, field management, harvest time, primary processing in the producing area, deep processing, storage, and transportation, etc.…”

Section: Introductionmentioning

confidence: 99%

Growth years and post-harvest processing methods have critical roles on the contents of medicinal active ingredients of Scutellaria baicalensis

Bai

Yang

Cao

et al. 2020

Industrial Crops and Products

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“…Moreover, the elevated pressure occurred due to microwaves inside the cell wall enhances micro explosions which could release the solute (Yingngam & Brantner, 2018). The yields are starting to decrease when the power level increases beyond 420 W. This is due to the higher microwave power promotes degradation of thermo sensitive phenolic compounds (Nabet et al, 2019).…”

Section: Resultsmentioning

confidence: 99%

A holistic approach for microwave assisted solvent extraction of phenolic compounds from Ficus benghalensis fruits and its phytochemical profiling

Radhakrishnan

Venkatachalam

2020

J Food Process Engineering

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Ficus benghalensis is a fig species spread throughout Asia, especially India, which finds its place in the tradition Indian system of medicines for their renowned protective properties. This study explores the extraction and identification of phytochemicals from the fruits of Ficus benghalensis using a time‐saving nonconventional technique of microwave assisted solvent extraction (MASE). The influence of independent variables (viz., solid‐solvent ratio, microwave power and irradiation time) on the maximum total phenolic content (TPC) and total flavonoid content (TFC) values was analyzed and optimized using response surface methodology (RSM) with a Box–Behnken Design. The maximum values of TPC (340.14 ± 0.34 mg/g) and TFC (413.64 ± 0.19 mg/g) were found at a shorter extraction time of 5 min, solid‐solvent ratio of 1:17 g/ml and microwave power of 420 W. The GC chromatogram was used for the phenolic distribution analysis and screening of the secondary metabolites. The GC spectra showed the presence of 26 biologically active secondary metabolites. 7‐tetradecenal (Z) (42.14%) was the predominant compound followed by n‐hexadecanoic acid (20.61%) and octadecanoic acid (14.07%). These compounds, along with others reportedly exhibit anticancer, antioxidant, anti‐diabetic, and antibacterial activities, thereby validating the traditional uses of the Ficus benghalensis fruit as a pharmaceutical supplement. Practical application The outcome of this work shows a time‐saving method of phytochemical extraction which can be used for extracting valuable metabolites from Ficus benghalensis fruits. Moreover, findings from this research work will aid as a baseline to facilitate future studies in the isolation and purification of the identified pharmaceutically active phytochemicals present in the Ficus benghalensis fruit extract. This can be further used to increase the fruits' bioprospecting.

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Optimization of microwave-assisted extraction recovery of bioactive compounds from Origanum glandulosum and Thymus fontanesii

Cited by 50 publications

References 43 publications

Extraction Processes Affect the Composition and Bioavailability of Flavones from Lamiaceae Plants: A Comprehensive Review

Extraction Processes Affect the Composition and Bioavailability of Flavones from Lamiaceae Plants: A Comprehensive Review

Growth years and post-harvest processing methods have critical roles on the contents of medicinal active ingredients of Scutellaria baicalensis

A holistic approach for microwave assisted solvent extraction of phenolic compounds from Ficus benghalensis fruits and its phytochemical profiling

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