Optimization of high intensity interval exercise in coronary heart disease

Guiraud, Thibaut; Juneau, Martin; Nigam, Anil; Gayda, Mathieu; Meyer, Philippe; Mekary, Saïd; Paillard, François; Bosquet, Laurent

doi:10.1007/s00421-009-1287-z

Cited by 84 publications

(66 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…peripheral and skeletal muscle adaptations) which may be applicable for older CAD patients (Gibala et al 2006;McKay et al 2009). At present, however, more research is required to determine the optimal modalities and doses of exercise and timecourse to adaptations to provide the greatest health benefits in patients with CAD (Fletcher et al 2001;Guiraud et al 2009). …”

Section: Discussionmentioning

confidence: 98%

“…There is currently a need to more thoroughly investigate and elucidate the modalities and dosages of exercise that can be prescribed to elicit safe, expeditious and peak recovery in patients with CAD (Fletcher et al 2001;Guiraud et al 2009). To our knowledge, the evidence-base for IT in cardiac patients has not been systematically reviewed to date.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Interval training for patients with coronary artery disease: a systematic review

2010

View full text Add to dashboard Cite

Interval training (IT) may induce physiological adaptations superior to those achieved with conventional moderate-intensity continuous training (MCT) in patients with coronary artery disease (CAD). Our objectives were (1) to systematically review studies which have prescribed IT in CAD, (2) to summarize the findings of this research including the safety and physiological benefits of IT, and (3) to identify areas for further investigation. A systematic review of the literature using computerized databases was performed. The search yielded two controlled trials and five randomized controlled trials (RCTs) enrolling 213 participants. IT prescribed in isolation or in combination with resistance training was shown to induce significant and clinically important physiological adaptations in cardiac patients. IT was also shown to improve cardiorespiratory fitness (e.g. VO(2max), VO(2AT)), endothelial function, left ventricle morphology and function (e.g. ejection fraction) to a significantly greater extent when compared with conventional MCT. No adverse cardiac or other life-threatening events occurred secondary to exercise participation in these studies. However, these findings must be interpreted with caution, as methodological limitations were present in all trials reviewed. In conclusion, robustly designed RCTs with thorough and standardized reporting are required to determine the risk and benefits of IT in the broader cardiac patient population. Further research is required to determine optimal IT protocols for the use in cardiac rehabilitation programmes, potentially contributing to novel exercise prescription guidelines for this patient population.

show abstract

Section: Discussionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Interval training for patients with coronary artery disease: a systematic review

2010

View full text Add to dashboard Cite

show abstract

“…In patients with coronary artery disease and heart failure, it has been suggested that short bouts of high-intensity exercise (100% of maximal aerobic power) such as 15 s for people with CAD and 30 s for people with HF (with passive recovery phases of the same duration between bouts, ratio 1:1) are optimal for obtaining benefits and improving adherence [26]. It is possible that these combinations are also adequate for people with hypertension as shown by Sosner et al [25], but more research is needed in order to establish the most appropriate training regime.…”

Section: Dose Of Exerciseementioning

confidence: 99%

Exercise for Hypertension

Chulvi‐Medrano¹,

José²,

Tortosa-Martínez³

et al. 2016

Fitness Medicine

View full text Add to dashboard Cite

High blood pressure (HBP) does not cause discomfort but still, you need to take care of and treat it. Otherwise, over time, it can damage the heart, kidneys, brain, and eyes. Lifestyle changes are essential in HBP, and physical activity is a parameter of great influence. In order to achieve the benefits derived from physical activity, it must be adequately prescribed, an aspect that will be developed in this chapter. The first section addresses the physiopathology of hypertension, with special interest in the pathological mechanisms that may induce hypertension, devices for monitoring blood pressure (BP), and an overview of the particularities that present hypertension in the presence of other pathologies and over the life span. Second section focuses on exercise prescription for hypertensive people, exploring each type of exercise that has been proved to be effective. We discuss for each type of exercise, the benefits, mechanisms involved in these benefits, the appropriate dose of exercise, and other methodological considerations including risk management issues. We conclude with a clinical case study. A detailed exercise training program will be developed for this particular case study in order to try to bridge the gap between theory and practice.

show abstract

“…As this thesis contains a focus on high intensity exercise training and this has previously been suggested to be unsafe for certain individuals, (127) Nephrologist alone. However, the literature indicates inclusion of an exercise professional in these multi-disciplinary teams has previously been omitted.…”

Section: Safety Of Exercise Trainingmentioning

confidence: 99%

“…In fact using target heart rates may limit the capacity of the patient to train at a high intensity. It has been suggested by Guiraud et al (2010) that manipulating walking or running velocity to maintain heart rate in a target zone may lead to a decreased VO 2 max as a result of cardiovascular drift. (127) Indeed, using an RPE rather than heart rate target may be desirable for some CKD patients.…”

Section: Assessing Intensity Of Exercisementioning

confidence: 99%

Exercise and lifestyle intervention and high intensity interval training in patients with chronic kidney disease

Beetham¹

View full text Add to dashboard Cite

Chronic kidney disease (CKD) patients have a shorter life expectancy than healthy individuals, from the premature development of cardiovascular disease due to traditional and non-traditional risk factors. It is therefore pertinent that management of CKD be aimed at modifying these cardiovascular disease risk factors. Exercise therapy, in particular aerobic exercise, in the end stage kidney disease population has been shown to decrease cardiovascular disease risk factors and subsequent cardiovascular disease. However, Section 2 contains the second trial that investigated the feasibility and efficacy of a 12 week HIIT program in CKD patients. Recruitment for the HIIT study was through participants who had completed the LM3 study.Chapter 1 provides an introduction to the studies, including the aims of the thesis. Topics reviewed include; pathophysiology of CKD, exercise capacity, autonomic dysfunction, haemoglobin, muscle atrophy, oxidative stress, inflammation, blood lipids and HIIT. Section 1 starts with the detailed methods of the LM3 study (Chapter 2). Further methods applicable to specific studies are reported in the relevant chapter.Chapter 3 investigates the determinants of reduced muscle strength at baseline through a cross-sectional analysis of the LM3 study. This study identified the association of oxidative 3 stress with low muscle strength and reduced lean mass. The relationship was independent of known influences on muscle mass and strength.The feasibility and determinants of the LI group participating in higher intensity exercise training in the first 12 months of the LM3 study was investigated in Chapter 4. The findings identified that higher intensity exercise training was indeed feasible in the CKD cohort, with the number of participants reporting higher intensity exercise increasing from 20% to 43%.Reported higher intensity exercise during the LI was also associated with the greatest exercise capacity at 12 months. Furthermore, the analysis identified haemoglobin to be the greatest predictor of individuals reporting higher intensity exercise.Chapter 5 investigates the agreement between creatinine and cystatin-C estimated glomerular filtration rate (eGFR) measurements in patients completing 12 months of the LM3 study. This chapter explores whether discrepancies in the CKD Epidemiology Collaboration (CKD-EPI)cystatin-C, CKD-EPIcreatinine and modification of diet in renal disease (MDRD) eGFR equations occur after an exercise intervention. It was identified that cystatin-C based eGFR measurements were considerably lower than creatinine based eGFR measurements. Despite this discrepancy at baseline, the agreement between the different GFR estimates did not change after exercise training.Chapter 6 contains the main study from LM3, which investigates the changes in cardiorespiratory fitness, exercise capacity, functional capacity, blood biochemistry, anthropometry measures and other cardiovascular disease risk factors after 3 years of LI compared to the control group. The primary finding from this...

show abstract

Optimization of high intensity interval exercise in coronary heart disease

Cited by 84 publications

References 31 publications

Interval training for patients with coronary artery disease: a systematic review

Interval training for patients with coronary artery disease: a systematic review

Exercise for Hypertension

Exercise and lifestyle intervention and high intensity interval training in patients with chronic kidney disease

Contact Info

Product

Resources

About