Purpose. To reduce the risks of accidents and injuries on the basis of vocational selection of the stuff for work in the mining industry, as well as training and maintaining their skills of safe work. Methodology. To solve the problems considered in the article, the following were used: analysis of information from scientific and technical sources on the influence of psychophysiological factors on occupational injuries; correlation-regression analysis of statistical data on occupational injuries; experimental research on efficiency of miners work in laboratory and mine conditions at various physical activities. Findings. The article substantiates the role and necessity of conducting professional psychophysiological selection procedures for mining workers, monitoring their functional state. The methodology of professional psychophysiological selection procedures, innovative training and behavioral audit is proposed in order to increase the injury protection of workers. Innovative ways of training and maintaining the safe working skills of miners are explored. The role of modern gadgets with installed applications for assessing the severity of physical work in terms of heart rate is investigated. Originality. The novelty of this study is to substantiate a comprehensive approach to the preventive precautions against occupational injuries in the mining industry at the stages of personnel selection, training and further control of the consequences of production activities. Practical value. Principles are developed for selecting, training, and maintaining skills for the safe work of personnel for the mining industry.