“…Setting the design guidelines for CWs is a challenging task, owing to the complex and nonlinear nature of biological reactions and the inter-reliant physical, chemical, and biological parameters. , The P - k - C * first-order kinetic model is most frequently used for the design of HFCWs. , In addition to the inlet and outlet pollutant concentrations, the area calculation using the P - k - C * approach depends on the areal removal rate coefficient k . , These k values can be calculated from the observed kinetic parameters of field-scale systems as reported in our previous studies that carried out extensive statistical analysis of the large dataset pertaining to the performance of 74 HFCWs . However, the dependencies of the k value on multiple factors like temperature, depth of media, the concentration of pollutants, detention time, and design flow make their design extremely complex. , In our previous study, datasets were classified based on factors like organic loading rate, temperature, and depth, and they significantly reduced the standard deviations (SDs) of k values, decreasing them from 84.74 to 34.85%; 116.48 to 31.42%; and 114.70 to 36.89%, respectively, for the three subcategories (BOD, TN, TP). Further reduction of the SDs could not be achieved .…”