Optimization of calcium phosphate fine ceramic powders preparation

Sezanova, Kostadinka; Tepavitcharova, Stefka; Rabadjieva, D.; Gergulova, R.; Ilieva, Radost

doi:10.1063/1.4849310

Cited by 2 publications

(1 citation statement)

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“…To address this, new processing technologies need to be developed to preserve the initially obtained nanocrystals. Various biocompatible organic additives, such as natural polysaccharides (guar gum and xanthan gum), amino acids (glycine, alanine, and valine), and polyols (glycerin), have been proven to influence the composition and morphology of the obtained precursors, as well as the granulometric composition of their high-temperature phases [ 100 ]. The choice of modifiers aims to inhibit the growth of primary nuclei and improve the morphological characteristics of the particles.…”

Section: General Principles Of Bone Substitute Synthesismentioning

confidence: 99%

Synthetic Calcium–Phosphate Materials for Bone Grafting

Mishchenko,

Yanovska,

Kosinov

et al. 2023

Polymers

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Synthetic bone grafting materials play a significant role in various medical applications involving bone regeneration and repair. Their ability to mimic the properties of natural bone and promote the healing process has contributed to their growing relevance. While calcium–phosphates and their composites with various polymers and biopolymers are widely used in clinical and experimental research, the diverse range of available polymer-based materials poses challenges in selecting the most suitable grafts for successful bone repair. This review aims to address the fundamental issues of bone biology and regeneration while providing a clear perspective on the principles guiding the development of synthetic materials. In this study, we delve into the basic principles underlying the creation of synthetic bone composites and explore the mechanisms of formation for biologically important complexes and structures associated with the various constituent parts of these materials. Additionally, we offer comprehensive information on the application of biologically active substances to enhance the properties and bioactivity of synthetic bone grafting materials. By presenting these insights, our review enables a deeper understanding of the regeneration processes facilitated by the application of synthetic bone composites.

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Section: General Principles Of Bone Substitute Synthesismentioning

confidence: 99%