Abstract:Gelatin from yellowfin tuna (Thunnus albacares) dorsal skin was optimized for adhesive strength to plywood using surface response methodology of a central composite design with a dependent variable of adhesive strength (Y, kg f /cm 2 ) and two independent variables of gelatin concentration (X 1 , %) and hardening time (X 2 , hrs). From the above design, a maximum adhesive strength of 49.84 kg f /cm 2 was obtained under the optimal treatment condition of 15.85% gelatin concentration and 25.68 hr hardening time.… Show more
“…Gelatin by itself has adhesive properties and has been considered a nontoxic alternative for solvent-based glue. 42 But with crosslinked gelatin, adhesiveness can be increased depending on the substrate bonded to the gelatin. Chen et al 43 demonstrated the potential of gelatin mixed with TGase as an adhesive to retinal tissue.…”
In this study, we developed an injectable gelatin-transglutaminase (TGase) gel for cell delivery. The procedure provides a minimally invasive approach to deliver cells into tissue in a manner that improves localization. The results indicate gelatin-TGase to be noncytotoxic and to have adhesive properties that help localize and prevent the scattering of the cells after delivery. The in situ crosslinking between gelatin chains and endogenous collagen can create a strong attachment between the gel and tissue extracellular matrix, preventing cells from dissipation. The gelatin-TGase was also shown to maintain the carried cells to be viable and proliferative. Finally, through the adjustment of the enzymatic crosslinker concentration, the release rate of the cells into the surrounding tissue after injection was demonstrated to be controllable.
“…Gelatin by itself has adhesive properties and has been considered a nontoxic alternative for solvent-based glue. 42 But with crosslinked gelatin, adhesiveness can be increased depending on the substrate bonded to the gelatin. Chen et al 43 demonstrated the potential of gelatin mixed with TGase as an adhesive to retinal tissue.…”
In this study, we developed an injectable gelatin-transglutaminase (TGase) gel for cell delivery. The procedure provides a minimally invasive approach to deliver cells into tissue in a manner that improves localization. The results indicate gelatin-TGase to be noncytotoxic and to have adhesive properties that help localize and prevent the scattering of the cells after delivery. The in situ crosslinking between gelatin chains and endogenous collagen can create a strong attachment between the gel and tissue extracellular matrix, preventing cells from dissipation. The gelatin-TGase was also shown to maintain the carried cells to be viable and proliferative. Finally, through the adjustment of the enzymatic crosslinker concentration, the release rate of the cells into the surrounding tissue after injection was demonstrated to be controllable.
“…(e) TG and (f) DTG of gelatin, GT, GD, GP, and GDP. (g) The tensile strength of bonded wood using gelatin, GDP, soy-based, cellulose-based, chitosan-based, and gelatin-based adhesives. (h) Degradation of the GDP film in the soil.…”
Section: Resultsmentioning
confidence: 99%
“…The GDP adhesive exhibited dry bonding strength and wet bonding strength of 5.52 MPa (improved by 57.72% compared to gelatin) and 4.71 MPa (improved by 1780% compared to gelatin), respectively, when bonded to wood. The bonding strength of the GDP adhesive to wood is also higher than the reported adhesives based on soy, 45 cellulose, 46 chitosan, 47 and gelatin 48 (Figure 7g).…”
“…L = 93.73, a = -0.12 b = 0.11 (Choi and Regenstein, 2000;Zhou et al, 2006;Yang et al, 2007). , (Cho et al, 2005;Yoon et al, 2008). , (Montero et al, 1990;Bateman et al, 1996;Gómez mez-Guillén et al, 2002).…”
The present study examined the physical properties of biofilms manufactured from yellowfin tuna Thunnus albacares skin gelatin with the aim of developing a biofilm from fisheries by-products to replace mammalian sources. The physical properties of biofilms from yellowfin tuna gelatin were compared with those of biofilms from porcine gelatin. The yellowfin tuna gelatin biofilm exhibited higher tensile strength (69.08 MPa) and greater elongation (14.32%) than did porcine gelatin biofilm (50.50 MPa and 10.21%, respectively). The E and YI (yellowness index) Huntercolor values of yellowfin tuna gelatin biofilm were threefold and 15-fold higher, respectively, than values for porcine gelatin biofilm. The opacity value of yellowfin tuna gelatin biofilm was higher than that of porcine gelatin biofilm. The stability against water of yellowfin tuna gelatin biofilm was lower than that of porcine gelatin biofilm at pH 3 to pH 11. Thermogravimetric analysis (TGA) indicated that the thermal stability of the biofilms was about 270˚C for porcine gelatin biofilm and about 250˚C for yellowfin tuna gelatin biofilm.
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