“…By using achiral substrates, such as chloroacetaldehyde and acetaldehyde, DERA catalyzes a sequential aldol addition that results in an enantiomerically pure lactol, (3 R ,5 R )‐6‐chloro‐2,4,6‐trideoxyhexose . This 2,4,6‐trideoxyhexose is a valuable chiral synthon for HMG‐CoA reductase inhibitors, collectively known as statins, and used for the production of cholesterol‐lowering drugs, such as atorvastatin and rosuvastatin .…”