Optimised extraction of antioxidant polyphenols from Satureja thymbra using newly designed glycerol-based natural low-transition temperature mixtures (LTTMs)

Jancheva, Magdalena; Grigorakis, Spyros; Loupassaki, Sofia; Makris, Dimitris P.

doi:10.1016/j.jarmap.2017.01.002

Cited by 32 publications

(29 citation statements)

References 30 publications

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“…The liquid-to-solid ratio (R L/S ) was set at 35 mL g −1 , which was an average level within the optimum range of 29.5 to 36.2 mL g −1 found for polyphenol extraction from Satureja thymbra with DES [20]. Extraction temperature was maintained at 55 • C, because higher temperatures may not favour increased polyphenol yield and extraction time was 60 min, which according to kinetic investigations, appeared sufficiently long to prevent variances that could stem from incomplete extraction [21].…”

Section: Extraction Efficiencymentioning

confidence: 99%

Combination of Lactic Acid-Based Deep Eutectic Solvents (DES) with β-Cyclodextrin: Performance Screening Using Ultrasound-Assisted Extraction of Polyphenols from Selected Native Greek Medicinal Plants

et al. 2017

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Abstract:A series of novel L-lactic acid-based deep eutectic solvents (DES) were tested for polyphenol extraction performance, using organically grown, native Greek medicinal plants. The extractions were ultrasonically-assisted and the effect of the addition of β-cyclodextrin (β-CD) as extraction booster was also tested, at a concentration of 1.5% (w/v). The estimation of total polyphenol yield (Y TP ) suggested that DES composed of L-lactic acid and nicotinamide and L-lactic acid and L-alanine, both at a molar ratio of 7:1, are promising solvents giving significantly higher yields compared with 60% (v/v) aqueous ethanol and water. However, when β-CD was combined with DES comprised of L-lactic acid and ammonium acetate (molar ratio 7:1), the extraction yields obtained in some instances were equal of even higher. The pattern was not consistent when the yield in total flavonoids (Y TFn ) was considered, indicating water, 60% (v/v) aqueous ethanol and L-lactic acid:sodium acetate (molar ratio 7:1) to be the most efficient solvents. In this case, the effect of β-CD was of rather lower magnitude. The examination of the antioxidant activity of the extracts generated showed that there is a close correlation mainly with their concentration in total polyphenols.

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Section: Extraction Efficiencymentioning

confidence: 99%

Combination of Lactic Acid-Based Deep Eutectic Solvents (DES) with β-Cyclodextrin: Performance Screening Using Ultrasound-Assisted Extraction of Polyphenols from Selected Native Greek Medicinal Plants

et al. 2017

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confidence: 97%

“…Yet, RL/S of 36.2 mL g −1 has also been reported [15]. It should be stressed that optima RL/S determined for polyphenol extraction with conventional solvents may reach up to 100-120 mL g −1 [20,21], but such With respect to C LTTM , it has been suggested that the amount of water required depends on the polarity of the solute (polyphenols), with flavonoid glycosides, such as rutin, being more soluble in LTTMs with a higher water proportion, compared with its aglycone quercetin [12].…”

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confidence: 99%

“…Additionally, as many LTTMs are rather quite viscous, appropriate viscosity tuning may be achieved through water incorporation, to facilitate extraction efficiency [14]. On the other hand, water content as high as 63.8% (v/v) has been used in glycerol-based LTTMs for the extraction of polyphenolic antioxidants [15]. However, water proportion exceeding 50% may involve danger of LTTM disintegration and loss of their peculiar properties [16].…”

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confidence: 99%

“…Recently, it was shown that yield of polyphenol extraction from red grape pomace dropped sharply by switching T from 60 to 70 • C, to recover partly at 80 • C [23]. The effect of T was studied more thoroughly in another recent examination, where an apparent anti-Arrhenius behaviour was revealed [15]. To explain this phenomenon, it was supported that increasing T beyond a certain limit, there might be decomposition of the LTTM, which would lead to weakening of their capacity to solubilise the solute.…”

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confidence: 99%

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Ultrasound-Assisted Extraction of Polyphenolic Antioxidants from Olive (Olea europaea) Leaves Using a Novel Glycerol/Sodium-Potassium Tartrate Low-Transition Temperature Mixture (LTTM)

et al. 2017

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Abstract:Olive leaves (OLL) represent a major waste generated during the production of olive oil, but there is a great potential for their valorization, because they provide important content in polyphenolic phytochemicals, which possess several bioactivities. In spite of the high number of studies dealing with polyphenol recovery from olive leaves, green processes involving environmentally benign solvents are scarce. In this study, a novel renewable natural low-transition temperature mixture (LTTM), composed of glycerol and sodium-potassium tartrate, was tested for its efficient ability to extract polyphenolic substances from OLL. The extraction process was optimised by using response surface methodology and the maximum yield in total polyphenols was 26.75 ± 3.22 mg caffeic acid equivalents per g dry weight, achieved with 50% (v/v) aqueous LTTM, liquid-to-solid ratio of 45 mL g −1 and at 73 • C. The LTTM was proven to be equally effective with 60% aqueous methanol, but it displayed inferior antioxidant properties. Liquid chromatography-diode array-mass spectrometry analyses revealed no significant qualitative differences between the LTTM and the aqueous methanolic extract.

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Extraction of Plant and Algal Polyphenols Using Eutectic Solvents

Percevault

Limanton

Gauffre

et al. 2020

Environmental Chemistry for a Sustainable World

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Optimised extraction of antioxidant polyphenols from Satureja thymbra using newly designed glycerol-based natural low-transition temperature mixtures (LTTMs)

Cited by 32 publications

References 30 publications

Combination of Lactic Acid-Based Deep Eutectic Solvents (DES) with β-Cyclodextrin: Performance Screening Using Ultrasound-Assisted Extraction of Polyphenols from Selected Native Greek Medicinal Plants

Combination of Lactic Acid-Based Deep Eutectic Solvents (DES) with β-Cyclodextrin: Performance Screening Using Ultrasound-Assisted Extraction of Polyphenols from Selected Native Greek Medicinal Plants

Ultrasound-Assisted Extraction of Polyphenolic Antioxidants from Olive (Olea europaea) Leaves Using a Novel Glycerol/Sodium-Potassium Tartrate Low-Transition Temperature Mixture (LTTM)

Extraction of Plant and Algal Polyphenols Using Eutectic Solvents

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