2019
DOI: 10.1016/j.msec.2019.04.017
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Optimisation of grafted phosphorylcholine-based polymer on additively manufactured titanium substrate for hip arthroplasty

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Cited by 17 publications
(14 citation statements)
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“…Furthermore, additively manufactured titanium alloys have been considered in the field of biomedical engineering [ 97 , 98 ], however, the selective laser melting process introduces high surface roughness due to partially melted particles which limits their use as hip implants [ 99 ]. Ghosh et al [ 99 ] have therefore, modified the surface of the fabricated titanium implants with 2-methacryloyoxyethyl phosphorylcholine polymer. It was crucial to achieve a homogenous graft of the polymer on the implant surface, to minimise the friction and wear impact.…”
Section: Spectroscopy and Its Application In Am Techniquesmentioning
confidence: 99%
“…Furthermore, additively manufactured titanium alloys have been considered in the field of biomedical engineering [ 97 , 98 ], however, the selective laser melting process introduces high surface roughness due to partially melted particles which limits their use as hip implants [ 99 ]. Ghosh et al [ 99 ] have therefore, modified the surface of the fabricated titanium implants with 2-methacryloyoxyethyl phosphorylcholine polymer. It was crucial to achieve a homogenous graft of the polymer on the implant surface, to minimise the friction and wear impact.…”
Section: Spectroscopy and Its Application In Am Techniquesmentioning
confidence: 99%
“…202 Ghosh et al also modified the commonly used a titanium alloy (Ti6Al4V) with an MPC polymer with a uniform surface, less roughness, and low cell attachment to fulfill the requirement of hip arthroplasty. 203 Implantable glucose sensors are very useful for monitoring the blood glucose level of diabetics; however, they still lack in vivo long-term reliability owing to the inflammation and fibrosis around the sensors, which both decrease their sensitivity (blocking glucose transportation) and shorten their lifetime. To address this problem, Wang et al developed a hydrogel coating incorporated with pH-sensitive molecularly imprinted polymer (MIP) nanospheres.…”
Section: Implant Materialsmentioning
confidence: 99%
“…In this regard, SLM has been widely used to fabricate the implant with a complex structure that patients need directly. Extensive studies have been reported, showing that the titanium-based implants produced by SLM exhibit excellent mechanical properties, compared with their traditionally manufactured counterparts [ 15 ], resulting from the rapid solidification-induced refined microstructure [ 16 , 17 ]. F.B et al confirmed that, due to the high cooling rate, the presence of harder microstructural constituents in Ti6Al4V, produced by SLM, leads to a higher wear resistance than hot pressing and casting specimen [ 18 ].…”
Section: Introductionmentioning
confidence: 99%