Optimisation extraction procedure and identification of phenolic compounds from fractional extract of corn silk (Zea mays hair) using LC-TOF/MS system

Nurraihana, H.; Ishak, Wan Rosli Wan; Sabreena, S.; Norfarizan-Hanoon, N. A.

doi:10.1007/s11694-018-9799-z

Cited by 15 publications

(14 citation statements)

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“…The present result shows that the PRF is more effective than metformin for the protection of HUVECs from high glucose. This protective effect might be due to phenolic compounds, which are present at a higher level in this fraction as reported in our previous study [ 15 ]. The PRF contained 22 phenolic compounds comprising of 21 flavonoids and one chalcone.…”

Section: Discussionsupporting

confidence: 69%

“…The PRF contained 22 phenolic compounds comprising of 21 flavonoids and one chalcone. The flavonoids detected in this fraction are classified into flavones, flavonols, flavone C-glycoside, flavonol O-glycosides, flavanols, and isoflavonoids [ 15 ]. Previous studies have reported that phenolic compounds, such as α-mangostin and maysin, had shown a protective effect against high glucose-induced damage in HUVECs [ 16 , 17 , 18 , 19 ].…”

Section: Discussionmentioning

confidence: 99%

“…Four batches of fresh baby corn comprising a total of 50 kg were purchased in October 2016, November 2016, April 2017 and May 2017. The fraction was prepared according to our previous study [ 15 ]. Briefly, the fresh corn silk was detached from the fruit stalks and then oven-dried (Memmert, Schwabach, Germany) at 55 °C for 48 h. The dried corn silk was ground into a powder form, using a food grinder (Tommy Tech, Shenzhen, China).…”

Section: Methodsmentioning

confidence: 99%

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Potential Effect of Polyphenolic-Rich Fractions of Corn Silk on Protecting Endothelial Cells against High Glucose Damage Using In Vitro and In Vivo Approaches

2021

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Endothelial cell dysfunction is considered to be one of the major causes of vascular complications in diabetes. Polyphenols are known as potent antioxidants that can contribute to the prevention of diabetes. Corn silk has been reported to contain polyphenols and has been used in folk medicine in China for the treatment of diabetes. The present study aims to investigate the potential protective role of the phenolic-rich fraction of corn silk (PRF) against injuries to vascular endothelial cells under high glucose conditions in vitro and in vivo. The protective effect of PRF from high glucose toxicity was investigated using human umbilical vein endothelial cells (HUVECs). The protective effect of PRF was subsequently evaluated by using in vivo methods in streptozotocin (STZ)-induced diabetic rats. Results showed that the PRF significantly reduced the cytotoxicity of glucose by restoring cell viability in a dose-dependent manner. PRF was also able to prevent the histological changes in the aorta of STZ-induced diabetic rats. Results suggested that PRF might have a beneficial effect on diabetic patients and may help to prevent the development and progression of diabetic complications such as diabetic nephropathy and atherosclerosis.

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Section: Discussionsupporting

confidence: 69%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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Potential Effect of Polyphenolic-Rich Fractions of Corn Silk on Protecting Endothelial Cells against High Glucose Damage Using In Vitro and In Vivo Approaches

2021

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“…1 Thn. 2020 DOI: http://doi.org/10.26877/jiphp.v4i1.4056 4 21 jenis flavonoid (5 flavon, 3 flavonols, 3 flavon C-glikosida, 2 flavonol O-glikosida, 4 flavanols, 4 isoflavonoid) dan satu jenis kalkon (Nurraihana et al, 2018).…”

Section: Senyawa Bioaktif Rambut Jagung Fenolmentioning

confidence: 99%

POTENSI TEH HERBAL RAMBUT JAGUNG (Zea mays L.) SEBAGAI SUMBER ANTIOKSIDAN: KAJIAN PUSTAKA

Syawal

Laeliocattleya

2020

JIPHP

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Rambut jagung merupakan sekumpulan kepala putik yang berasal dari bunga betina tanaman jagung, berbentuk seperti benang maupun rambut yang berwarna kekuningan. Fungsi dari rambut jagung adalah untuk menjebak serbuk sari pada saat penyerbukan. Rambut jagung memiliki senyawa bioaktif yang dapat bertindak sebagai antioksidan apabila dikonsumsi. Manfaat tersebut dapat diperoleh melalui produk olahan rambut jagung, salah satunya adalah teh herbal dari rambut jagung. Teh herbal merupakan minuman yang berasal dari bahan alami yang bermanfaat bagi tubuh. Teh herbal biasanya dibuat dari rempah-rempah atau bagian dari tanaman dan dikonsumsi dalam bentuk teh yaitu seduhan bagian tanaman yang direbus atau diseduh dengan air mendidih.

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“…Previous researchers have conducted research using several varieties of plants to prevent and dissolved a kidney stones, such as Orthosiphon stamineus, Strobilanthes crispa, Ceiba pentandra, corn silk, and Cucumis sativus [6][7][8][9][10] . Some study reported that rich flavonoid plant has an activity in dissolving a kidney stones by forming a chelate complex with calcium kidney stones [11][12] .…”

Section: Introductionmentioning

confidence: 99%

Activity of Ethyl Acetate Fraction of Celery Herb (Apium Graveolens L.) on Creatinine and Urea Level in Ethylene Glycol Induced Rats

Nainggolan¹,

Sinaga²,

Sinaga³

et al. 2018

Int. Res. J. Pharm.

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The utilization of celery by the community in Indonesia was known as a seasoning, particularly in soups to enrich the taste of food, the potential effect of celery herb especially as herbal medicine both in preventive or curative therapy are not widely known yet. The celery herb is rich in flavonoids content which has potential effect to dissolve kidney stones.The purpose of this study was to determine the effect of ethyl acetate (Apium graveolens L) fraction on urea and creatinine levels in male wistar rats induced by ethylene glycol. The in vivo test was conducted on male Wistar rats that divided into 6 groups. Group I as a normal control without treatment, Group II as a negative control induced by ethylene glycol, Group III as a positive control was given Batugin Elixir, Group IV, V and VI were given ethyl acetate fraction of celery at 50, 100 and 150 mg / kgbw respectively. Blood sample was collected through cardiac puncture method. The results showed that ethyl acetate fraction of celery herb had an effective activity at a dose of 150 mg / kgbw which was significantly different to the negative control group (P <0.05) measured by a reduction of urea and creatinine level on male wistar rats induced by ethylene glycol.

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Optimisation extraction procedure and identification of phenolic compounds from fractional extract of corn silk (Zea mays hair) using LC-TOF/MS system

Cited by 15 publications

References 50 publications

Potential Effect of Polyphenolic-Rich Fractions of Corn Silk on Protecting Endothelial Cells against High Glucose Damage Using In Vitro and In Vivo Approaches

Potential Effect of Polyphenolic-Rich Fractions of Corn Silk on Protecting Endothelial Cells against High Glucose Damage Using In Vitro and In Vivo Approaches

POTENSI TEH HERBAL RAMBUT JAGUNG (Zea mays L.) SEBAGAI SUMBER ANTIOKSIDAN: KAJIAN PUSTAKA

Activity of Ethyl Acetate Fraction of Celery Herb (Apium Graveolens L.) on Creatinine and Urea Level in Ethylene Glycol Induced Rats

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