Optimisation and biological activities of bioceramic robocast scaffolds provided with an oxygen-releasing coating for bone tissue engineering applications

Touri, Maria; Moztarzadeh, Fathollah; Osman, Noor Azuan Abu; Mozafari, Masoud

doi:10.1016/j.ceramint.2018.09.247

Cited by 40 publications

(34 citation statements)

References 59 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Their results showed sustained oxygen release, which subsequently promoted bone ingrowth with improved osteoblast cell viability and proliferation under hypoxic conditions [92]. In a later study, they also showed the scaffold's antibacterial properties, with enhanced inhibitory effects against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) [91].…”

Section: D-printed Protein-and Oxygen-releasing Biomaterialsmentioning

confidence: 95%

“…A lack of oxygen can eventually lead to lower medical treatment efficiency, increased inflammation and infection, and tissue necrosis [89]. Thus, developing oxygen-releasing biomaterials has become a significant field of interest over the last few years [90][91][92]. For example, Touri et al 3D printed scaffolds containing 60% hydroxyapatite (HA) and 40% betatricalcium phosphate (β-TCP).…”

Section: D-printed Protein-and Oxygen-releasing Biomaterialsmentioning

confidence: 99%

See 1 more Smart Citation

From oral formulations to drug-eluting implants: using 3D and 4D printing to develop drug delivery systems and personalized medicine

et al. 2021

View full text Add to dashboard Cite

Since the start of the Precision Medicine Initiative by the United States of America in 2015, interest in personalized medicine has grown extensively. In short, personalized medicine is a term that describes medical treatment that is tuned to the individual. One possible way to realize personalized medicine is 3D printing. When using materials that can be tuned upon stimulation, 4D printing is established. In recent years, many studies have been exploring a new field that combines 3D and 4D printing with therapeutics. This has resulted in many concepts of pharmaceutical devices and formulations that can be printed and, possibly, tailored to an individual. Moreover, the first 3D printed drug, Spritam®, has already found its way to the clinic. This review gives an overview of various 3D and 4D printing techniques and their applications in the pharmaceutical field as drug delivery systems and personalized medicine.

show abstract

Section: D-printed Protein-and Oxygen-releasing Biomaterialsmentioning

confidence: 95%

Section: D-printed Protein-and Oxygen-releasing Biomaterialsmentioning

confidence: 99%

From oral formulations to drug-eluting implants: using 3D and 4D printing to develop drug delivery systems and personalized medicine

et al. 2021

View full text Add to dashboard Cite

show abstract

“…82 Low degradation favors hard tissue applications, because PCL can sustain tissue growth longer; however, hypoxia, encapsulation, and porosity problems need to be addressed, and tissue necrosis needs to be avoided. 84,85 Therefore, tailoring PCL biodegradation for biomedical applications is a complex question because it might lead to detriment of mechanical properties and release of toxic waste, undermining biocompatibility during the implantation period. 9…”

Section: Biodegradationmentioning

confidence: 99%

Polycaprolactone usage in additive manufacturing strategies for tissue engineering applications: A review

et al. 2021

View full text Add to dashboard Cite

Polycaprolactone (PCL) has been extensively applied on tissue engineering because of its low‐melting temperature, good processability, biodegradability, biocompatibility, mechanical resistance, and relatively low cost. The advance of additive manufacturing (AM) technologies in the past decade have boosted the fabrication of customized PCL products, with shorter processing time and absence of material waste. In this context, this review focuses on the use of AM techniques to produce PCL scaffolds for various tissue engineering applications, including bone, muscle, cartilage, skin, and cardiovascular tissue regeneration. The search for optimized geometry, porosity, interconnectivity, controlled degradation rate, and tailored mechanical properties are explored as a tool for enhancing PCL biocompatibility and bioactivity. In addition, rheological and thermal behavior is discussed in terms of filament and scaffold production. Finally, a roadmap for future research is outlined, including the combination of PCL struts with cell‐laden hydrogels and 4D printing.

show abstract

“…The fabrication of biomedical scaffolds with micron-size channels and struts were successfully developed using robocasting. Touri et al [101] developed biomedical scaffolds using hydroxyapatite (HA) and beta-tricalcium phosphate (β-TCP) powder mixture. The robocasting process was used to fabricate porous 3D lattice structures.…”

Section: Materials Extrusionmentioning

confidence: 99%

Micro-fabrication of ceramics: Additive manufacturing and conventional technologies

et al. 2021

View full text Add to dashboard Cite

Ceramic materials are increasingly used in micro-electro-mechanical systems (MEMS) as they offer many advantages such as high-temperature resistance, high wear resistance, low density, and favourable mechanical and chemical properties at elevated temperature. However, with the emerging of additive manufacturing, the use of ceramics for functional and structural MEMS raises new opportunities and challenges. This paper provides an extensive review of the manufacturing processes used for ceramic-based MEMS, including additive and conventional manufacturing technologies. The review covers the micro-fabrication techniques of ceramics with the focus on their operating principles, main features, and processed materials. Challenges that need to be addressed in applying additive technologies in MEMS include ceramic printing on wafers, post-processing at the micro-level, resolution, and quality control. The paper also sheds light on the new possibilities of ceramic additive micro-fabrication and their potential applications, which indicates a promising future.

show abstract

Optimisation and biological activities of bioceramic robocast scaffolds provided with an oxygen-releasing coating for bone tissue engineering applications

Cited by 40 publications

References 59 publications

From oral formulations to drug-eluting implants: using 3D and 4D printing to develop drug delivery systems and personalized medicine

From oral formulations to drug-eluting implants: using 3D and 4D printing to develop drug delivery systems and personalized medicine

Polycaprolactone usage in additive manufacturing strategies for tissue engineering applications: A review

Micro-fabrication of ceramics: Additive manufacturing and conventional technologies

Contact Info

Product

Resources

About