Optimierte NMR‐Methode zur Bestimmung der Konfiguration chemisch äquivalenter vicinaler Protonen

Luy, Burkhard; Hauser, G.; Kirschning, Andreas; Glaser, Steffen J.

doi:10.1002/ange.200390306

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Unclassified

Year Published

2004

2016

Publication Types

Select...

Article5

Relationship

Self Cite4

Independent1

Authors

Journals

Cited by 5 publications

(2 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Phase‐sensitive absorption (States‐TPPI) is possible by cycling ϕ 1 . Alternatively, simple t 1 ‐incrementation can be applied with the processing procedure described previously in references 22, 23.…”

mentioning

confidence: 99%

Stretched Gelatin Gels as Chiral Alignment Media for the Discrimination of Enantiomers by NMR Spectroscopy

2005

Self Cite

View full text Add to dashboard Cite

show abstract

mentioning

confidence: 99%

Stretched Gelatin Gels as Chiral Alignment Media for the Discrimination of Enantiomers by NMR Spectroscopy

2005

Self Cite

View full text Add to dashboard Cite

show abstract

“…Alternativ kann eine einfache t 1 ‐Inkrementierung mit der in Lits. 22, 23 beschriebenen Prozessierungsmethode durchgeführt werden.…”

unclassified

Gestreckte Gelatine als chirales Orientierungsmedium zur Unterscheidung von Enantiomeren durch NMR‐Spektroskopie

2005

Self Cite

View full text Add to dashboard Cite

show abstract

Synthesis of Aromatic Retinoids and Curcuminoids and Evaluation of their Antiproliferative, Antiradical, and Anti-inflammatory Activities

Morzycki

Rárová²,

Grúz³

et al. 2016

ChemistryOpen

View full text Add to dashboard Cite

Natural retinoids and curcuminoids are known for their broad spectrum of biological properties, such as antioxidant, anti‐inflammatory, antitumor, and so forth. In this work, a convenient synthesis of aromatic retinoids and curcuminoids from vinyl or allyl ketones, and the corresponding alcohols, using olefin metathesis as a key reaction, was elaborated. The best yields and diastereoselectivities were obtained from allylic or homoallylic alcohols by employing the two‐step cross‐metathesis/oxidation procedure. The synthesized analogues were tested for their antiproliferative activity on human cancer cell lines of various origin (leukemia CEM, adenocarcinoma MCF7, cervical carcinoma HeLa) as well as for their antioxidant and anti‐inflammatory activity in vitro. All examined derivatives exhibited strong anti‐inflammatory activity in vitro without affecting cell viability. They also showed strong cytotoxicity against leukemia cell line CEM, except for 18 and 35. The antioxidant activity of the tested compounds was rather weak.

show abstract

Optimierte NMR‐Methode zur Bestimmung der Konfiguration chemisch äquivalenter vicinaler Protonen

Cited by 5 publications

References 27 publications

Stretched Gelatin Gels as Chiral Alignment Media for the Discrimination of Enantiomers by NMR Spectroscopy

Stretched Gelatin Gels as Chiral Alignment Media for the Discrimination of Enantiomers by NMR Spectroscopy

Gestreckte Gelatine als chirales Orientierungsmedium zur Unterscheidung von Enantiomeren durch NMR‐Spektroskopie

Synthesis of Aromatic Retinoids and Curcuminoids and Evaluation of their Antiproliferative, Antiradical, and Anti-inflammatory Activities

Contact Info

Product

Resources

About