Optimal weekly frequency of 308-nm excimer laser treatment in vitiligo patients

Hofer, Angelika; Hassan, A.S.; Legat, Franz J.; Kerl, Helmut; Wolf, Peter

doi:10.1111/j.1365-2133.2004.06321.x

Cited by 80 publications

(70 citation statements)

References 13 publications

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“…The optimum frequency of phototherapy is two or three times per week [26]. However, final repigmentation does not correlate with the frequency of phototherapy but correlate with the total number of treatments [27,28]. In this study, UVB phototherapy was performed at 2-week interval.…”

Section: Discussionmentioning

confidence: 99%

A comparative study of combined treatment with fractional carbon dioxide and targeted ultraviolet B phototherapy for facial vitiligo

et al. 2016

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Facial vitiligo is associated with considerable psychological impact. The management is challenging and requires multidisciplinary treatment. Adding fractional carbon dioxide (CO2) to the conventional treatment has been reported as an effective modality. This study aimed to evaluate the efficacy of combined fractional CO2 laser, targeted ultraviolet B (UVB) phototherapy, and topical steroid on facial vitiligo. A prospective, randomized, split face study was conducted on 14 patients with symmetrical non-segmental facial vitiligo. Ten sessions of fractional CO2 laser was performed on the lesions on one side of face with 2-week interval. Immediately after laser, the lesions on both side of face were treated with 10 sessions of 2-week interval targeted UVB phototherapy and twice daily application of topical 0.05 % clobetasol propionate cream. The patients were followed up for 12 weeks after the last treatment. Clinical improvement was graded by blinded dermatologists and patients using a quartile grading scale. Twelve out of 14 patients completed the study. The degree of improvement was not different between both sides in nine patients. One patient showed more improvement on the combined laser side, and two patients showed inferior results on the combined laser side. Two patients with lesser improvement on the laser-treated side had positive Koebner phenomenon on the non-facial area. The combined treatment with laser, targeted UVB, and topical steroids are not superior to targeted UVB and topical steroids in facial vitiligo. Furthermore, laser may retard the response to the standard treatment in patients with Koebner phenomenon on non-treated areas.

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Section: Discussionmentioning

confidence: 99%

A comparative study of combined treatment with fractional carbon dioxide and targeted ultraviolet B phototherapy for facial vitiligo

et al. 2016

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“…The treatment protocol we adapted for this trial was based on previous AA treatment studies [7,8,10,11] and vitiligo treatment protocols [17,18,19]. Whether the treatment protocol is optimal for AA patients is not clarified, but this protocol has already proven its immunosuppressive effects in cases of various skin diseases such as vitiligo and psoriasis.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of 308-nm Excimer Laser Therapy in Treating Alopecia Areata, Determined by Examining the Treated Sides of Selected Alopecic Patches

et al. 2015

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Background: Some studies have reported the use of 308-nm excimer laser therapy for treating alopecia areata (AA); however, the effectiveness of this therapy on a theoretical basis has not yet been comparatively analyzed. Objectives: To determine the therapeutic effect of excimer laser therapy on AA. Methods: One alopecic patch was divided into control and treated sides in 10 patients with AA. Then, 308-nm excimer laser therapy was administered twice a week for 12 weeks. Photograph and phototrichogram analyses were performed. Results: Photographic assessments by both dermatologists and individuals of the general population showed objective improvements after excimer laser therapy. On the treated side, the hair count and hair diameter had statistically increased after treatment. However, only the hair diameter was found to be significantly high in the treated half when it was compared with the control side. Conclusion: The 308-nm excimer laser has a therapeutic effect on AA, which is proven by photograph and phototrichogram analysis by a side-by-side comparison.

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“…Dar bant UVB, haftada iki ya da üç kere uygulanır. Dar bant UVB'de iki farklı uygulama sıklığını etkinlik açısından karşılaştıran bir çalışma olmamakla birlikte, excimer lazer ile yapılan bir çalışmada, haftada üç uygulamanın daha hızlı repigmentasyona yol açtığı, ancak sonuçta elde edilen repigmentasyonun tedavi sıklığı ile değil, toplam seans sayısı ile ilişkili olduğu bulunmuştur (6). Tedaviye sabit bir başlangıç dozu ile ya da minimal eritem dozunun %50-70'i ile başlanabilir.…”

Section: Vitiligoda Fototerapiunclassified

Current Approach to Phototherapy Applications in Dermatology Practice: Part 2. Phototherapy in Vitiligo, Mycosis Fungoides, Atopic Dermatitis, Sclerosing Diseases and Psoriasis

Gençosmanoğlu¹

2017

tdd

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Optimal weekly frequency of 308-nm excimer laser treatment in vitiligo patients

Cited by 80 publications

References 13 publications

A comparative study of combined treatment with fractional carbon dioxide and targeted ultraviolet B phototherapy for facial vitiligo

A comparative study of combined treatment with fractional carbon dioxide and targeted ultraviolet B phototherapy for facial vitiligo

Effectiveness of 308-nm Excimer Laser Therapy in Treating Alopecia Areata, Determined by Examining the Treated Sides of Selected Alopecic Patches

Current Approach to Phototherapy Applications in Dermatology Practice: Part 2. Phototherapy in Vitiligo, Mycosis Fungoides, Atopic Dermatitis, Sclerosing Diseases and Psoriasis

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