Optimal Volume Assessment for Serous Fluid Cytology

Mikou, Panagiota; Christofidis, Konstantinos; Pergaris, Alexandros; Keramari, Panagiota

doi:10.1016/j.jasc.2022.07.050

Cited by 1 publication

(10 citation statements)

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“…have reported their retrospective experience with different effusion specimens. Evaluation of pericardial effusions has been reported in 10 studies, five of which reported ROM assessments, with the number of samples/patients ranging from 64 to 574 24 . The estimated ROM for each category was: ND, 0.0%–100.0%; NFM, 1.3%–17.4%; AUS, 0.0%–35.0%; SFM, 57.1%–100.0%; and MAL, 89.3%–100.0% 24 .…”

Section: Introductionmentioning

confidence: 99%

“…Evaluation of pericardial effusions has been reported in 10 studies, five of which reported ROM assessments, with the number of samples/patients ranging from 64 to 574 24 . The estimated ROM for each category was: ND, 0.0%–100.0%; NFM, 1.3%–17.4%; AUS, 0.0%–35.0%; SFM, 57.1%–100.0%; and MAL, 89.3%–100.0% 24 . The categories SFM and MAL included 20.0%–62.5% of the total cases and provided a diagnosis of malignancy with exceedingly high probability 24 .…”

Section: Introductionmentioning

confidence: 99%

“…The estimated ROM for each category was: ND, 0.0%–100.0%; NFM, 1.3%–17.4%; AUS, 0.0%–35.0%; SFM, 57.1%–100.0%; and MAL, 89.3%–100.0% 24 . The categories SFM and MAL included 20.0%–62.5% of the total cases and provided a diagnosis of malignancy with exceedingly high probability 24 . There were 13 studies that included pleural effusions, 10 of which reported ROM evaluation, with the number of samples/patients ranging from 350 to 2454 24 .…”

Section: Introductionmentioning

confidence: 99%

“…The categories SFM and MAL included 20.0%–62.5% of the total cases and provided a diagnosis of malignancy with exceedingly high probability 24 . There were 13 studies that included pleural effusions, 10 of which reported ROM evaluation, with the number of samples/patients ranging from 350 to 2454 24 . The estimated ROM for each category was: ND, 0.0%–57.1%; NFM, 1.8%–29.8%; AUS, 33.3%–62.3%; SFM, 76.2%–99.3%; and MAL, 90.2%–100.0% 24 .…”

Section: Introductionmentioning

confidence: 99%

“…There were 13 studies that included pleural effusions, 10 of which reported ROM evaluation, with the number of samples/patients ranging from 350 to 2454 24 . The estimated ROM for each category was: ND, 0.0%–57.1%; NFM, 1.8%–29.8%; AUS, 33.3%–62.3%; SFM, 76.2%–99.3%; and MAL, 90.2%–100.0% 24 . The categories SFM and MAL included 7.0%–65.6% of the total cases for studies with a reported ROM and provided a diagnosis of malignancy with a remarkably high probability for pleural effusions as well 24 .…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Risks of malignancy in the major nongynecologic cytopathology reporting systems: Critiques and discussions

Pusztaszeri,

Saieg,

Baloch

2024

Cancer Cytopathology

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The ever‐increasing popularity of standardized systems for reporting cytopathology has led in part to much attention to and importance of the risk stratification schemes, especially the risks of malignancy (ROMs), which are associated with the different diagnostic categories and upon which recommendations for clinical management are based. However, it is well known that the ROM calculations are based on retrospective reviews of the existing literature, representing a heterogeneous patient population, and are plagued by significant biases and variations. Statistically, the ROM represents the post‐test probability of malignancy, which changes with the test result and with the prevalence of malignancy (or pretest probability) in an individual practice setting and individual patient presentation. Therefore, the clinical utility of the ROM is questioned and likely needs a second look in the nongynecologic cytopathology reporting systems. In this communication, the authors discuss the status of the ROM estimates according to the most commonly used nongynecologic reporting systems, including for thyroid, salivary glands, and others, highlighting similarities and differences with a focus on the limitations of ROM estimates and their application in clinical practice.

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Section: Introductionmentioning

confidence: 99%