Optimal utilization of expanded criteria deceased donors for kidney transplantation

Karatzas, Theodore; Gompou, Athina; Bokos, John; Dimitroulis, Dimitrios; Boletis, John; Kostakis, A.; Kouraklis, Gregory; Zavos, G.

doi:10.1007/s11255-011-9930-0

Cited by 6 publications

(1 citation statement)

References 20 publications

(42 reference statements)

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“…Older deceased donors have been associated with a higher risk of graft failure [4][5][6][7]. This provides a rationale for incorporating broad recipient-donor age matching into kidney allocation algorithms to better align graft quality with life expectancy [8].…”

Section: Introductionmentioning

confidence: 99%

Living donor age and kidney transplant outcomes: an assessment of risk across the age continuum

2013

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SummaryDetailed data on living donor age, and its interplay with recipient age, in predicting allograft and recipient outcomes are wanting. We used the Scientific Registry of Transplant Recipients (2000Recipients ( -2009, n = 49 589) to assess the effect of living donor age on delayed graft function (DGF), total graft failure, death-censored graft failure, death with graft function, and graft failure with death as a competing risk using logistic and Cox proportional hazards models. Potential nonlinear associations were modeled using fractional polynomial functions. There was a significant 1.87-fold increase in the adjusted odds of DGF in the oldest versus youngest age groups. The 10-year adjusted hazard ratios (HR) for total graft failure, deathcensored graft failure, and death with graft function increased in a nonlinear fashion across the range of living donor age studied. Graft failure was most accentuated in the youngest recipient age groups in competing risk models. Adjustment for renal function at 6-and 12-months post-transplant markedly attenuated the association between living donor age and graft/patient outcomes. Our findings confirm the important influence of living donor age on transplant outcomes and provide detailed estimates of risk across the living donor age continuum.

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Section: Introductionmentioning

confidence: 99%

Living donor age and kidney transplant outcomes: an assessment of risk across the age continuum

2013

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The impact of slow graft function on graft outcome is comparable to delayed graft function in deceased donor kidney transplantation

Shin

Koo

et al. 2015

Int Urol Nephrol

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Clinical Outcomes in Kidney Transplantation Patients From Deceased Donors With Acute Kidney Injury

Jung

Park

Kim

et al. 2013

Transplantation Proceedings

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Optimal utilization of expanded criteria deceased donors for kidney transplantation

Abstract: ECDs significantly increased the kidney pool and can be utilized safely if adequate measures are taken.

Cited by 6 publications

References 20 publications

Living donor age and kidney transplant outcomes: an assessment of risk across the age continuum

Living donor age and kidney transplant outcomes: an assessment of risk across the age continuum

The impact of slow graft function on graft outcome is comparable to delayed graft function in deceased donor kidney transplantation

Clinical Outcomes in Kidney Transplantation Patients From Deceased Donors With Acute Kidney Injury

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