Optimal Timing of Surgery for Patients with Active Infective Endocarditis

Kitai, Takeshi; Masumoto, Akihide; Okada, Taiji; Koyama, Tadaaki; Furukawa, Yutaka

doi:10.1016/j.ccl.2021.01.002

Cited by 6 publications

(3 citation statements)

References 93 publications

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“…In this case report, the patient had a significant size of mitral valve vegetation of >1 cm, and findings were consistent with embolization of the spleen. Unfortunately, in-hospital mortality for valve replacement surgery can be as high as 20%, and in E. faecalis infection, it is not associated with improved survival [3,15]. Therefore, this was not indicated for our patient as co-morbidities such as COPD and cirrhosis posed a very high risk.…”

Section: Discussionmentioning

confidence: 97%

Enterococcus faecalis Endocarditis of All Four Native Valves: A Case Report

Pinheiro Alves,

Overbey,

Jin

et al. 2024

Cureus

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Enterococcus faecalis is commonly implicated in Infective Endocarditis (IE), resulting in remarkable morbidity and mortality. We present an unusual case documenting the clinical course and outcome of an elderly female patient who developed quadruple valve endocarditis due to Enterococcus faecalis infection. She presented with altered mental status, resulting in hospitalization, and was found to have bacteremia complicated by endocarditis, epidural abscess, discitis, and splenic infarction. Urinalysis was consistent with bacterial infection two days before being admitted to the hospital. Unfortunately, despite aggressive therapeutic regimens, the patient died. This is one of the few documented endocarditis cases involving all heart valves. It reviews the importance of maintaining a high index of clinical suspicion for assessing IE, with a low threshold for performing a transesophageal echocardiogram as a diagnostic tool.

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Section: Discussionmentioning

confidence: 97%

Enterococcus faecalis Endocarditis of All Four Native Valves: A Case Report

Pinheiro Alves,

Overbey,

Jin

et al. 2024

Cureus

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“…Infective endocarditis (IE) is a serious condition and represents a rare cause of stroke. The incidence is approximately 3–10 cases per 100.000 [ 1 ]. The modified Duke Criteria considering clinical, imaging, and bacteriological findings are the standard for diagnosis of IE [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

“…Although there have been improvements in diagnostics and therapy, both diagnosis and treatment remain difficult and mortality in IE patients remains high. The in-hospital mortality of IE is approximately 18–25% and 1-year mortality is up to 40% [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

Infective endocarditis and stroke: when does it bleed? A single center retrospective study

Nitsch

Samani

Silaschi

et al. 2023

Neurol. Res. Pract.

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Background Infective endocarditis (IE) is a serious condition with a high mortality, represents a rare cause of stroke and an increased risk of intracranial hemorrhage. In this single center study, we characterize stroke patients with IE. We were interested in risk factors for intracranial hemorrhage and outcome of patients with intracranial hemorrhage compared to patients with ischemic stroke. Methods Patients with IE and symptomatic ischemic stroke or intracranial hemorrhage admitted to our hospital between January 2019 and December 2022 were included in this retrospective study. Results 48 patients with IE and ischemic stroke or intracranial hemorrhage were identified. 37 patients were diagnosed with ischemic stroke, 11 patients were diagnosed with intracranial hemorrhage. The intracranial hemorrhage occurred within the first 12 days after admission. We identified Staphylococcus aureus detection and thrombocytopenia as risk factors for hemorrhagic complications. An increased in-hospital mortality in patients with intracranial hemorrhage (63.6% vs. 22%, p = 0.022) was found, whereas patients with ischemic stroke and patients with intracranial hemorrhage do not differ regarding favorable clinical outcome (27% vs. 27.3%, p = 1.0). 27.3% patients with intracranial hemorrhage and 43.2% patients with ischemic stroke underwent cardiac surgery. Overall, 15.7% new ischemic strokes occurred after valve reconstruction, whereas no new intracranial hemorrhage was observed. Conclusions We found an increased in-hospital mortality in patients with intracranial hemorrhage. Beside thrombocytopenia, we identified S. aureus detection as a risk factor for intracranial hemorrhage.

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Mitral Valve Infective Endocarditis

Moorjani

2023

Springer Surgery Atlas Series

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Optimal Timing of Surgery for Patients with Active Infective Endocarditis

Cited by 6 publications

References 93 publications

Enterococcus faecalis Endocarditis of All Four Native Valves: A Case Report

Enterococcus faecalis Endocarditis of All Four Native Valves: A Case Report

Infective endocarditis and stroke: when does it bleed? A single center retrospective study

Mitral Valve Infective Endocarditis

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