Optimal single 3T MR imaging sequence for HDR brachytherapy of cervical cancer

Dempsey, Claire; Arm, Jameen; Best, Leah; Govindarajulu, G.; Capp, Anne; O’Brien, Peter C.

doi:10.5114/jcb.2014.41528

Cited by 6 publications

(2 citation statements)

References 30 publications

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“…Currently, 2D or 3D T2 FSE sequences are used to plan treatment for gynecologic cancers, and these techniques are motion sensitive. 13 The 3D sequences, which take longer to acquire and involve phase encoding along both phase and slice directions, are more susceptible to motion. Therefore, increasing the images' sharpness will help detect tumor margins (Figs.…”

Section: Discussionmentioning

confidence: 99%

A Feasibility Study on Deep Learning Reconstruction to Improve Image Quality With PROPELLER Acquisition in the Setting of T2-Weighted Gynecologic Pelvic Magnetic Resonance Imaging

Saleh

Virarkar

Javadi

et al. 2023

J Comput Assist Tomogr

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Objectives: Evaluate deep learning (DL) to improve the image quality of the PROPELLER (Periodically Rotated Overlapping Parallel Lines with Enhanced Reconstruction technique) for 3 T magnetic resonance imaging of the female pelvis.Methods: Three radiologists prospectively and independently compared non-DL and DL PROPELLER sequences from 20 patients with a history of gynecologic malignancy. Sequences with different noise reduction factors (DL 25%, DL 50%, and DL 75%) were blindly reviewed and scored based on artifacts, noise, relative sharpness, and overall image quality. The generalized estimating equation method was used to assess the effect of methods on the Likert scales. Quantitatively, the contrast-to-noise ratio and signal-to-noise ratio (SNR) of the iliac muscle were calculated, and pairwise comparisons were performed based on a linear mixed model. P values were adjusted using the Dunnett method. Interobserver agreement was assessed using the κ statistic. P value was considered statistically significant at less than 0.05.Results: Qualitatively, DL 50 and DL 75 were ranked as the best sequences in 86% of cases. Images generated by the DL method were significantly better than non-DL images ( P < 0.0001). Iliacus muscle SNR on DL 50 and DL 75 was significantly better than non-DL images ( P < 0.0001). There was no difference in contrast-to-noise ratio between the DL and non-DL techniques in the iliac muscle. There was a high percent agreement (97.1%) in terms of DL sequences' superior image quality (97.1%) and sharpness (100%) relative to non-DL images. Conclusion:The utilization of DL reconstruction improves the image quality of PROPELLER sequences with improved SNR quantitatively.

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Section: Discussionmentioning

confidence: 99%

A Feasibility Study on Deep Learning Reconstruction to Improve Image Quality With PROPELLER Acquisition in the Setting of T2-Weighted Gynecologic Pelvic Magnetic Resonance Imaging

Saleh

Virarkar

Javadi

et al. 2023

J Comput Assist Tomogr

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“…37 Some authors report the implementation into clinical routine of MR sequences for 3 T units. 42,43 Adequate patient preparation is required prior to MR scan. Although the preparation procedure may differ between centers, the use of antispasmodics is generally recommended in order to reduce bowel motion during scanning.…”

Section: Practical Considerations About the Use Of Mr For Cervix Cancmentioning

confidence: 99%

Review of strategies for MRI based reconstruction of endocavitary and interstitial applicators in brachytherapy of cervical cancer

Richart

Carmona-Meseguer²,

García-Martinez

et al. 2018

Reports of Practical Oncology & Radiotherapy

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Another strategy to improve the reconstruction process is based on the incorporation of MR markers, such as small pellets, to be used as anchor points. Many institutions employ computed tomography (CT) as a supporting image modality. The registration of CT and MR image sets should be carefully performed, and its uncertainty previously assessed. Besides, an important research work is being carried out regarding the use of ultrasound and electromagnetic tracking technologies.

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Implications for dosimetric changes when introducing MR-guided brachytherapy for small volume cervix cancer: a comparison of CT and MR-based treatments in a single centre

Dempsey¹,

Govindarajulu

Sridharan

et al. 2014

Australas Phys Eng Sci Med

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To evaluate cervix brachytherapy dosimetry with the introduction of magnetic resonance (MR) based treatment planning and volumetric prescriptions and propose a method for plan evaluation in the transition period. The treatment records of 69 patients were reviewed retrospectively. Forty one patients were treated using computed tomography (CT)-based, Point A-based prescriptions and 28 patients were treated using magnetic resonance (MR)-based, volumetric prescriptions. Plans were assessed for dose to Point A and organs at risk (OAR) with additional high-risk clinical target volume (HR-CTV) dose assessment for MR-based brachytherapy plans. ICRU-38 point doses and GEC-ESTRO recommended volumetric doses (D2cc for OAR and D100, D98 and D90 for HR-CTV) were also considered. For patients with small HR-CTV sizes, introduction of MR-based volumetric brachytherapy produced a change in dose delivered to Point A and OAR. Point A doses fell by 4.8 Gy (p = 0.0002) and ICRU and D2cc doses for OAR also reduced (p < 0.01). Mean Point A doses for MR-based brachytherapy treatment plans were closer to those of HR-CTV D100 for volumes less than 20 cm(3) and HR-CTV D98 for volumes between 20 and 35 cm(3), with a significant difference (p < 0.0001) between Point A and HR-CTV D90 doses in these ranges. In order to maintain brachytherapy dose consistency across varying HR-CTV sizes there must be a relationship between the volume of the HR-CTV and the prescription dose. Rather than adopting a 'one size fits all' approach during the transition to volume-based prescriptions, this audit has shown that separating prescription volumes into HR-CTV size categories of less than 20 cm(3), between 20 and 35 cm(3), and more than 35 cm(3) the HR-CTV can provide dose uniformity across all volumes and can be directly linked to traditional Point A prescriptions.

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Optimal single 3T MR imaging sequence for HDR brachytherapy of cervical cancer

Cited by 6 publications

References 30 publications

A Feasibility Study on Deep Learning Reconstruction to Improve Image Quality With PROPELLER Acquisition in the Setting of T2-Weighted Gynecologic Pelvic Magnetic Resonance Imaging

A Feasibility Study on Deep Learning Reconstruction to Improve Image Quality With PROPELLER Acquisition in the Setting of T2-Weighted Gynecologic Pelvic Magnetic Resonance Imaging

Review of strategies for MRI based reconstruction of endocavitary and interstitial applicators in brachytherapy of cervical cancer

Implications for dosimetric changes when introducing MR-guided brachytherapy for small volume cervix cancer: a comparison of CT and MR-based treatments in a single centre

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