“…Therefore, the true optimal design may be obtained by inspection of the optimality for each sequence. Cheng and Yu (2003) give detailed derivation for this boundary. For the owsheet without energy integration, the results indicate that, for both sequences, the optimal paths start from the corner of heavy reactant (B) when z C is low (z C → 0) and, as the z C increases, they converge toward the center line which means equally distributed reactants (i.e., z A = z B ).…”