Optimal Dietary Conditions for Hemoccult Testing

Macrae, Finlay; John, David; Caligiore, Paul; Taylor, Leanne S.; Legge, J W

doi:10.1016/s0016-5085(82)80253-9

Cited by 125 publications

(13 citation statements)

References 12 publications

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“…A major disadvantage of Guaiac tests is the fact that they are not specific for human blood and can produce false‐positive results when meat, fruit, or vegetables containing peroxidase have been ingested. Also bleeding in the upper gastrointestinal (GI) tract secondary to aspirin and non‐steroidal anti‐inflammatory drugs (NSAIDs) can produce false‐positive Guaiac‐based tests 16 . This may lead to contraindicate colonoscopic examinations thus increasing the cost and risk of screening programmes.…”

Section: Introductionmentioning

confidence: 99%

Comparative evaluation of a new bedside faecal occult blood test in a prospective multicentre study

Hoepffner

Shastri

Hanisch

et al. 2005

Aliment Pharmacol Ther

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SUMMARY BackgroundFaecal occult blood testing is an established method of colorectal neoplasia screening. Guaiac-based tests are limited by poor patient compliance, low sensitivity, specificity and positive predictive value. Newer immunochemical-based tests, accurate but tedious, require a well-established laboratory set up. There is need for simpler immunochemical tests that can be performed at the out-patient clinic.

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Section: Introductionmentioning

confidence: 99%

Comparative evaluation of a new bedside faecal occult blood test in a prospective multicentre study

Hoepffner

Shastri

Hanisch

et al. 2005

Aliment Pharmacol Ther

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“…The issue of slide storage and rehydration of FOBT is also controversial. Rehydration has been shown to enhance sensitivity and restore positive reactions (Macrae, 1982). However, the false positive rate also dramatically increases with hydrations (Cohen, 1989;Simon, 1985).…”

Section: Fecal Occult Bloodmentioning

confidence: 99%

Mass Colorectal Cancer Screening

Burris

McGovern

1993

AAOHN Journal

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I n the United States colorectal cancer is the third leading cause of cancer related deaths (ACS, 1993). It is estimated that 57,000 Americans will die from colorectal cancer in 1993 alone (ACS, 1993). It has the distinction of being the most common type of cancer that affects males and females at approximately equal rates (ACS, 1980). In 1990 alone, more than 60,000 Americans died from colon or rectal cancers, and more than 150,000 new cases were diagnosed (DHHS, 1990; Eddy, 1990). In Minnesota, 2,471 cases of colorectal cancer were diagnosed in 1988, resulting in a rate of 41.9 per 100,000 for colon cancer and 18.1 per 100,000 for rectal cancer (males), which correlated closely with rates for the rest of the country (MDH, 1991). The overall 5 year survival rate for colon cancer approaches 90%, and is approximately 80% for rectal cancer (ACS, 1991), but only if the cancers are detected and treated while the lesions are still in the early, localized stage. However, because over 50% of the diagnoses are not made until after the disease is in a more advanced stage, half of the people who get this disease will die' from it (NCI, 1987). Besides the disease associated mortality, colorectal cancer and its

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“…Hemoccult positive results were obtained from stools with as little as 0.04 mg of hemoglobin per gram of stool Commercial Tests There are several companies that produce and market and stools with as much as 42. [51] found few falseplete one slide each for three consecutive bowel move-positive reactions among persons on an unrestricted diet, ments. The three-slide package is returned to the doctor's if the test slides were not rehydrated.…”

Section: It Was Not Until the Introduction Of The Impregnatedmentioning

confidence: 97%

The current status of early detection and screening for colorectal cancer

Mettlin

Cummings

1986

Seminars in Surgical Oncology

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There are several approaches to the early detection of colorectal cancer that currently are in use in various segments of the health care system. Herein, the status of cancer control research regarding symptom and risk factor assessment, sigmoidoscopy and colonoscopy, double contrast barium enema, and fecal occult blood testing is reviewed. In addition to the different technologies of early cancer detection, there are different models of disease control intervention. These include the routine clinical activities of primary care providers as well as programmatic screening of mass populations. The currently available techniques for early colorectal cancer detection appear better suited for existing patient care settings than for programs outside the direct supervision and follow-up of the health professional.

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Optimal Dietary Conditions for Hemoccult Testing

Cited by 125 publications

References 12 publications

Comparative evaluation of a new bedside faecal occult blood test in a prospective multicentre study

Comparative evaluation of a new bedside faecal occult blood test in a prospective multicentre study

Mass Colorectal Cancer Screening

The current status of early detection and screening for colorectal cancer

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