Optimal control of tumor–immune system interaction with treatment

Strategi Kontrol Optimal Model SIQR pada Penyebaran Penyakit Campak

“…Sebagai tambahan kajian, bahwa kontrol optimal digunakan sebagai alat untuk menggambarkan dinamika solusi penanganan penyebaran penyakit kanker serviks (Kristanti et al, 2020). Selanjutnya, sebagai penguat akan pentingnya masalah kontrol optimal, penelitian dan analisis kontrol optimal diimplementasikan dalam pencegahan tumor, dengan variabel kontrolnya berupa proses imunoterapi dan kemoterapi (Trisilowati, 2021). Oleh karena itu, Fatmawati dkk melakukan perluasan model yang telah dikaji dengan penambahan variabel kontrol sebagai usaha penanganan penyakit campak.…”

Optimal Control for Fractional Order Dynamics of Tumor Growth

“…Some tumors can live in the body for years without causing any symptoms. Others can rapidly grow, invade, or spread, causing death in a short period of time [33].…”

“…CD8+ interacts with cells known as major histocompatibility complex (MHC) Class I molecules to ascertain when healthy cells are infected. Cytotoxic T -cells are triggered once the CD8+ receptor detects an infected cell [33]. Cytotoxic T-cells create substances that are intended to get rid of the infection.…”

“…Tumors are divided into two types: benign or noncancerous tumors and malignant or cancerous ones. Benign tumors include osteomas, neuromas, nevi, hemangiomas, and others, whereas malignant tumors include Sarcomas, Myelomas, Carcinomas, Lymphomas, and others [33]. Although benign tumors are frequently believed to be less dangerous than their invasive malignant peers because they do not spread to other tissues, it should be noted that the growth of a benign tumor can be dangerous (precancerous tumors) due to the obstruction of natural bodily functions.…”

“…Although benign tumors are frequently believed to be less dangerous than their invasive malignant peers because they do not spread to other tissues, it should be noted that the growth of a benign tumor can be dangerous (precancerous tumors) due to the obstruction of natural bodily functions. The ability of a malignant tumor to grow uncontrollably and invade or spread to other body tissues is one of its primary characteristics [33]. Tumor cells are transported by the circulatory or lymphatic systems and deposited in various locations throughout the body.…”