2014
DOI: 10.1016/j.cmpb.2013.09.002
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Optimal bone density distributions: Numerical analysis of the osteocyte spatial influence in bone remodeling

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Cited by 41 publications
(34 citation statements)
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“…Continuing work to identify whether the extent of the network varies across species, including extinct species, may also provide insights into how this network complexity has evolved [68][69][70][71]. Finally, as mathematical models of the biomechanical regulation of the skeleton become more comprehensive [49,[72][73][74][75][76][77][78][79][80][81], valid quantifications of the osteocyte network from the cellular to the whole organ scale will allow realistic predictions of this complex dynamic system and its emergent behaviours [82,83]. High-resolution 3D imaging of bone is improving, thus revealing new understandings of the function of the osteocyte network.…”
Section: Discussionmentioning
confidence: 99%
“…Continuing work to identify whether the extent of the network varies across species, including extinct species, may also provide insights into how this network complexity has evolved [68][69][70][71]. Finally, as mathematical models of the biomechanical regulation of the skeleton become more comprehensive [49,[72][73][74][75][76][77][78][79][80][81], valid quantifications of the osteocyte network from the cellular to the whole organ scale will allow realistic predictions of this complex dynamic system and its emergent behaviours [82,83]. High-resolution 3D imaging of bone is improving, thus revealing new understandings of the function of the osteocyte network.…”
Section: Discussionmentioning
confidence: 99%
“…Due to the high porosity, the Biot model should probably be modified, see e.g. [50][51][52][53][54][55][56][57][58], by adding a correction term which takes into account the microstructural effect [48,[59][60][61][62][63][64]. Strain gradient models (see e.g.…”
Section: Numerical Simulationsmentioning
confidence: 99%
“…They have also been used for modelling the trabecular architecture of bones [7], and for evaluating the bone density distribution [8]. Another problem connected with bone remodelling, which concerns the interaction of bone with resorbable biomaterial, has been addressed in [9][10][11].…”
Section: Introductionmentioning
confidence: 99%