Optimal Blood Pressure Control Improves Left Ventricular Torsional Deformation and Vascular Function in Newly Diagnosed Hypertensives: a 3-Year Follow-up Study

Tzortzis, Stavros; Ikonomidis, Ignatios; Triantafyllidi, H; Trivilou, Paraskevi; Pavlidis, George; Katsanos, Spyridon; Katogiannis, K; Birba, D; Thymis, J; Makavos, Georgios; Varoudi, Maria; Frogoudaki, Alexandra; Vrettou, Agathi‐Rosa; Vlastos, Dimitrios; Parissis, John; Lekakis, John

doi:10.1007/s12265-019-09951-9

Cited by 15 publications

(29 citation statements)

References 31 publications

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“…This is an important question and deserves to be answered in the near future. Recently published study showed that optimal blood pressure control improved LV longitudinal strain during the period of 3 years . This has been noticed also for some, but not all parameters of LV diastolic function remained the same .…”

mentioning

confidence: 76%

“…Recently published study showed that optimal blood pressure control improved LV longitudinal strain during the period of 3 years . This has been noticed also for some, but not all parameters of LV diastolic function remained the same . LV mass index significantly reduced over the follow‐up period, but this reduction was not associated with LV longitudinal strain improvement independently of blood pressure reduction, which was the independent predictor of longitudinal strain improvement in newly diagnosed hypertensive patients …”

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confidence: 85%

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Left ventricular strain and arterial hypertension: Is longitudinal strain ready for primetime?

Tadić

Cuspidi

2020

J of Clinical Hypertension

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More than one decade passed from the first studies regarding left ventricular (LV) mechanics in patients with arterial hypertension (AH). At the beginning, the assessment of LV strain was considered as a research tool, which was exclusively used in well-equipped echocardiographic laboratories. What is the situation nowadays and does LV strain still has status of "fancy gadget" or necessity in the evaluation of subclinical subtle cardiac damage in patients with AH?The first studies used tissue-Doppler derived LV strain and soon after speckle tracking imaging arrived and completely replaced tissue-Doppler strain technique. Pioneer investigations showed difference between physiological LV hypertrophy in athletes and pathological LV hypertrophy in AH patients using LV longitudinal strain. 1,2 However, studies that revealed LV strain deterioration in the young untreated hypertensive patients without LV hypertrophy broke the prejudice that LV hypertrophy is "conditio sine qua non" for LV strain reduction. 3The most of studies emphasized the effect of AH on LV longitudinal strain and impairment of LV circumferential and radial strains, if detected, was put aside. There are several reasons for this attitude of investigators. Namely, strain evaluation is unfortunately still vendor-dependent and this remains the most important limitation of this imaging technique for more than decade. A lot of effort was put in the attempt to establish similar kind of LV longitudinal strain calculation with different vendors, and nowadays, this difference is minimized, but still exists. 4 We are still far a way of establishing the same consensus in calculation of LV circumferential and radial strain. The other important reason that may explain focusing on LV longitudinal strain was the fact that most of vendors provided quick assessment only of LV longitudinal strain, whereas the evaluation of circumferential and radial strains required special software and therefore remained more scientific than clinical tool. The major problem was also setting proper cutoff values for all types of LV strain. This problem was almost overcome for LV longitudinal strain in the last couple of years, and current guidelines claimed that LV longitudinal strain should be >−20% in healthy persons. 5 However, the recommendation still considers −16% as the cutoff of normality. 5This only confirms uncertainty that still exists in this area and large gray zone of LV longitudinal strain (between −16% and −20%). We are not even close to make this kind of consensus for LV circumferential and radial strain. However, one thing is certain, when LV longitudinal strain assessment is made using the same vendor or software from the time of diagnosis through the whole follow-up, one could be certain that evaluation of strain is much more reproducible than calculation of LV ejection fraction over this period. 6 According to the physiological mechanics of LV systolic function, longitudinal dysfunction may serve as a marker at an early stage of myocardial damage, whereas the chang...

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confidence: 76%

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confidence: 85%

Left ventricular strain and arterial hypertension: Is longitudinal strain ready for primetime?

Tadić

Cuspidi

2020

J of Clinical Hypertension

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“…Therefore, we supposed that non‐DP might be a harmful factor in acute HA exposure. Previous studies found that LV twist and untwisting rate were significantly impaired in the hypertensive patients, always indicating damage of LV myocardial function 30 . Whether, there is more obvious structural damage in non‐DP patients compared with DP group remains to be confirmed.…”

Section: Discussionmentioning

confidence: 84%

“…Previous studies found that LV twist and untwisting rate were significantly impaired in the hypertensive patients, always indicating damage of LV myocardial function. 30 Whether, there is more obvious structural damage in non‐DP patients compared with DP group remains to be confirmed. Furthermore, the exact molecular mechanisms involved in various BP changes in the two groups remain unknown.…”

Section: Discussionmentioning

confidence: 95%

Blood pressure and left ventricular function changes in different ambulatory blood pressure patterns at high altitude

Chen

Yang

Liu

et al. 2021

J of Clinical Hypertension

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“…Novel sensitive methods of cardiac function are required to assess the effects of TEVAR-induced increase of arterial stiffness on cardiac function and to monitor the effects of antihypertensive treatment. Indeed, optimal blood pressure control has been shown to reduce arterial stiffening and improve myocardial deformation and coronary flow at 3 years of follow-up in hypertensives [10]. Thus, an adequate control of arterial hypertension post-TEVAR leading to reduction of arterial stiffening may be necessary to maintain a good cardiac function in the long-term.…”

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confidence: 99%

Changes in aortic stiffness and the hemodynamics following endovascular repair of the thoracic aorta of patients with blunt thoracic aortic injury

Moulakakis¹,

Ikonomidis

Manopoulos

et al. 2020

Vasa

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Optimal Blood Pressure Control Improves Left Ventricular Torsional Deformation and Vascular Function in Newly Diagnosed Hypertensives: a 3-Year Follow-up Study

Cited by 15 publications

References 31 publications

Left ventricular strain and arterial hypertension: Is longitudinal strain ready for primetime?

Left ventricular strain and arterial hypertension: Is longitudinal strain ready for primetime?

Blood pressure and left ventricular function changes in different ambulatory blood pressure patterns at high altitude

Changes in aortic stiffness and the hemodynamics following endovascular repair of the thoracic aorta of patients with blunt thoracic aortic injury

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