COMMENT & RESPONSEIn Reply We appreciate the interest of Jouffroy and Vivien in our study. 1 Given the reported failure rates and complications of prehospital needle decompression (PHND), the value of the intervention has been questioned. 2,3 Thus, we sought not to provide another detailed description in a case series but investigate in one of the largest populations undergoing PHND whether there is a potential outcome benefit to support further refinement and advancement of this technique. 1 A major limitation has been the difficulty of diagnosing tension pneumothorax in the field and the empirical nature of PHND, leading to a lack of comparative studies to establish effectiveness. While we acknowledge the assumptions in our comparison group of emergency tube thoracostomy raised here, we believe given the above difficulties, this is a group that potentially would have benefited from earlier chest decompression in the field given the current landscape of US prehospital medicine.We do agree that the lack of pulse oximetry is a limitation, but the Pennsylvania Trauma Outcome Study data set only added the admission data point in 2018 with nearly 75% missing values. As with any registry data set, the indications for most procedures including both PHND and tube thoracostomy are not recorded but require us to infer from available clinical information and diagnoses. We certainly agree that prehospital decompression in the right patient should be viewed as lifesaving and not wasted time; identifying critical lifesaving procedures is a top priority. The US emergency medical services system has several challenges, including heterogeneity in training, staffing, capabilities, and resources. Patients with tension pneumothorax from rural areas with longer transport times are most likely to benefit from PHND, but agencies in these areas are unfortunately the least likely to be able to afford and maintain an advanced prehospital ultrasonography program to aide in field identification.Given the potential benefit paired with high variability of PHND seen in our study, we agree this provides a strong impetus to focus on refining the indications, identification, education, and technique in terms of type of catheter, anatomic position, and role finger thoracostomy to further improve the care of injured patients. [4][5][6]