Optically Active Hybrid Materials Constructed from Helically Substituted Polyacetylenes

Abstract

Functional materials derived from synthetic helical polymers are attracting increasing interest. Helically substituted polyacetylenes (HSPAs) are especially interesting as typical artificial helical polymers. In recent years, we designed and prepared a series of functional materials based on HSPAs and inorganic materials. The target is to establish some novel hybrid materials that combine the superior properties of both. The examined inorganic materials include silica, graphene, and magnetic Fe3 O4 nanoparticles. Such new functional materials hold great promise and are expected to find practical applications, for instance, as chiral absorbents, chiral sensors, chiral selectors for inducing enantioselective crystallization, chiral catalysts towards asymmetric catalysis, and chiral carriers for enantioselective release. The Personal Account summarizes our major achievements in preparing optically active hybrid materials. We hope it will speed up progress in chiral-related research areas.

Synthesis of Multi Amino Acid Chiral Polymeric Microparticles for Enantioselective Chemistry

“…[18] The Deng, Jianping group has been very active in preparation and application of chiral polymeric and chiral inorganic-polymeric hybrid nanoparticles based on optically active helical polymers. [30][31][32][33][34][35][36][37][38][39] Further research in the area of chiral polymeric nanomaterials was conducted by O'Reilly and coworkers who developed new methods for synthesis of chiral micelles and nanoparticles for applications in organocatalysis. [40][41][42][43] In addition to this field advanced chiral polymers have been synthesized with grafted optically active helical polymeric structures and has been applied to chiral recognition.…”

Organocatalytic chiral polymeric nanoparticles for asymmetric aldol reaction

“…Deng and coworkers managed to form hybrid organic and inorganic CPPs based on optically active helical polymers. [17][18][19][20][21][22][23][24][25][26] One of the fastest growing elds in chemistry is organocatalysis which are formed by mostly natural products that does not have a metal which in substoichiometric amounts accelerates a reaction. 27 Catalyzed direct asymmetric aldol reaction comprising a nonactivated ketone as a nucleophile is one of the most useful reactions for the formation of C-C chains.…”

“…Deng and coworkers managed to form hybrid organic and inorganic CPPs based on optically active helical polymers. 17–26…”

Preparation and Applications of Chiral Polymeric Particles

“…Besides, the studies accomplished so far have demonstrated that the polymer chains in solid particles can still form helical structures. [20] Chiral polyacetylenic particles can be directly used, and the deficiencies of original polyacetylenes such as poor processibility, low solubility, low stability against heat and oxygen are thus anticipated to be circumvented accordingly. Thereby the progress in CPPs also helpfully promotes the advancements in non-chiral polyacetylenes.…”