Optical waveguide lightmode spectroscopy technique-based immunosensor development for aflatoxin B1 determination in spice paprika samples

Majer-Baranyi, Krisztina; Zalán, Zsolt; Mörtl, Mária; Juracsek, Judit; Szendrő, István; Székacs, András; Adányi, Nóra

doi:10.1016/j.foodchem.2016.05.089

Cited by 28 publications

(9 citation statements)

References 25 publications

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“…The same group applied the OWLS immunosensor to the analysis of AFB 1 in 60 spice paprika samples from different countries, finding that 16 samples were contaminated with AFB 1 , and 9 samples contained AFB 1 above the official maximum residue level (5 μg/kg) set by the European Commission. Excellent correlation was observed with the results obtained by ELISA and high-performance liquid chromatography (HPLC) with fluorescent detection [44].…”

Section: Fiber Optic and Evanescent Wave Biosensorsmentioning

confidence: 58%

Optical Biosensors for Label-Free Detection of Small Molecules

Peltomaa

Glahn-Martínez

Benito‐Peña

et al. 2018

Sensors

170

111

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Label-free optical biosensors are an intriguing option for the analyses of many analytes, as they offer several advantages such as high sensitivity, direct and real-time measurement in addition to multiplexing capabilities. However, development of label-free optical biosensors for small molecules can be challenging as most of them are not naturally chromogenic or fluorescent, and in some cases, the sensor response is related to the size of the analyte. To overcome some of the limitations associated with the analysis of biologically, pharmacologically, or environmentally relevant compounds of low molecular weight, recent advances in the field have improved the detection of these analytes using outstanding methodology, instrumentation, recognition elements, or immobilization strategies. In this review, we aim to introduce some of the latest developments in the field of label-free optical biosensors with the focus on applications with novel innovations to overcome the challenges related to small molecule detection. Optical label-free methods with different transduction schemes, including evanescent wave and optical fiber sensors, surface plasmon resonance, surface-enhanced Raman spectroscopy, and interferometry, using various biorecognition elements, such as antibodies, aptamers, enzymes, and bioinspired molecularly imprinted polymers, are reviewed.

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Section: Fiber Optic and Evanescent Wave Biosensorsmentioning

confidence: 58%

Optical Biosensors for Label-Free Detection of Small Molecules

Peltomaa

Glahn-Martínez

Benito‐Peña

et al. 2018

Sensors

170

111

View full text Add to dashboard Cite

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“…The OWLS technique has been applied for the detection of AFB1 in both competitive and in direct methods. Determination from barley and wheat flour samples well correlated with those with ELISA (Table III) [13], [14]. By using gold nanoparticles (AuNP), especially bio-AuNP-s, the sensitivity and the reusability were enhanced for the analysis of spiced paprika samples [15].…”

Section: Nanobiosensors For Mycotoxins and Toxins In Foodstuffmentioning

confidence: 99%

OWLS Based Nanosensors for Agro-Environmental and Food Safety

Adányi¹,

Szendrő²,

Székacs³

2017

JOAAT

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With globalized trade of food commodities, food safety and related environmental safety issues have become a central concern not only at national/regional levels, but all over the world. Consumers are concerned about food-borne pathogens and their toxic substances, including mycotoxins, as well as chemicals, including residues of pesticides and veterinary drugs. Environmental pollution may also lead to contamination of food/feed commodities grown in affected land. For the quick and reliable detection of hazardous substances, new types of sensors based on evanescent wave optical techniques on the rise to detect food-borne contaminants. Our results, obtained by Optical Waveguide Lightmode Spectroscopy (OWLS) based label-free immmunosensors used for determination of different chemical contaminants in food responsible for the risk of food poisoning, are presented. Measuring methods were investigated for the determination of herbicide active ingredient trifluralin and biomarker protein vitellogenin for monitoring the pollution with endocrine disrupting chemicals, as well as for different mycotoxins (aflatoxin, zearalenone, deoxynivalenol) and microbials. High specificity/selectivity of the sensitised surface coupled with high sensitivity of OWLS detection gives the possibility to develop immunosensors and microbial sensors in most cases with definitely lower limits of detection than those in traditionally used immunoassays in direct/competitive formats.  Index Terms-optical waveguide lightmode spectroscopy, nanobiosensor, agro-environmental safety, food safety I. EVANESCENT WAVE OPTICAL TECHNIQUES Nanotechnology has a multiple and rapidly expanding role in food industry. Nanomaterials are used in food production or inspection with their unique, nano-sized dispersity, or as novel methodologies utilizing Manuscript

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“…It should be noted that the small 1 g sample size used in this analysis should be further evaluated for sample homogeneity even for use in a qualitative screening test. Another new method utilising immunosensor technology was published using the optical waveguide lightmode spectroscopy (OWLS) technique for AFB 1 determination in paprika (Majer-Baranyi et al, 2016). This method was applied to the label-free detection of AFB 1 in a competitive immunoassay format.…”

Section: Mycotoxins In Botanicals and Spicesmentioning

confidence: 99%

Developments in mycotoxin analysis: an update for 2017-2018

Tittlemier¹,

Cramer

Dall’Asta

et al. 2019

WMJ

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This review summarises developments that have been published in the period from mid-2017 to mid-2018 on the analysis of various matrices for mycotoxins. Analytical methods to determine aflatoxins, Alternaria toxins, ergot alkaloids, fumonisins, ochratoxins, patulin, trichothecenes, and zearalenone are covered in individual sections. Advances in sampling strategies are discussed in a dedicated section, as are methods used to analyse botanicals and spices, and newly developed comprehensive liquid chromatographic-mass spectrometric based multi-mycotoxin methods. This critical review aims to briefly discuss the most important recent developments and trends in mycotoxin determination as well as to address limitations of the presented methodologies.

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Optical waveguide lightmode spectroscopy technique-based immunosensor development for aflatoxin B1 determination in spice paprika samples

Cited by 28 publications

References 25 publications

Optical Biosensors for Label-Free Detection of Small Molecules

Optical Biosensors for Label-Free Detection of Small Molecules

OWLS Based Nanosensors for Agro-Environmental and Food Safety

Developments in mycotoxin analysis: an update for 2017-2018

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