Optical sensors of volatile organic compounds for non-invasive diagnosis of diseases

Qu, Xiaoyun; Hu, Yaping; Xu, Chenggang; Li, Yue; Zhang, Lin; Huang, Qiao; Sadat Moshirian-Farahi, Sareh; Zhang, Jianmin; Xu, Xiahong; Liao, Ming; Fu, Yingchun

doi:10.1016/j.cej.2024.149804

Cited by 8 publications

(1 citation statement)

References 112 publications

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“…In addition to these chemical sensors, various types of chemical sensors employing combinations of different sensing elements such as metal–oxide–semiconductors (CMOSs), carbon nanotubes (CNTs), NPs and chemicals, and signal-transducing elements such as nanomaterial fabricated electrodes, LAPS, surface plasmon resonance (SPR), Raman spectroscopy, optic fiber, fluorescent spectrometry, and microfluidics to detect cells and diseases have been reported [ 38 , 39 , 40 , 41 ]. Moreover, new materials for target sensing are continuously being developed and applied to these sensor platforms due to the rapid advances in nanomaterials (NMs) and fabrication technologies.…”

Section: Chemical Sensor Systems For Cell Monitoringmentioning

confidence: 99%

The Biomedical Applications of Biomolecule Integrated Biosensors for Cell Monitoring

Song,

Hwang,

Jeon

et al. 2024

IJMS

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Cell monitoring is essential for understanding the physiological conditions and cell abnormalities induced by various stimuli, such as stress factors, microbial invasion, and diseases. Currently, various techniques for detecting cell abnormalities and metabolites originating from specific cells are employed to obtain information on cells in terms of human health. Although the states of cells have traditionally been accessed using instrument-based analysis, this has been replaced by various sensor systems equipped with new materials and technologies. Various sensor systems have been developed for monitoring cells by recognizing biological markers such as proteins on cell surfaces, components on plasma membranes, secreted metabolites, and DNA sequences. Sensor systems are classified into subclasses, such as chemical sensors and biosensors, based on the components used to recognize the targets. In this review, we aim to outline the fundamental principles of sensor systems used for monitoring cells, encompassing both biosensors and chemical sensors. Specifically, we focus on biosensing systems in terms of the types of sensing and signal-transducing elements and introduce recent advancements and applications of biosensors. Finally, we address the present challenges in biosensor systems and the prospects that should be considered to enhance biosensor performance. Although this review covers the application of biosensors for monitoring cells, we believe that it can provide valuable insights for researchers and general readers interested in the advancements of biosensing and its further applications in biomedical fields.

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Section: Chemical Sensor Systems For Cell Monitoringmentioning

confidence: 99%

The Biomedical Applications of Biomolecule Integrated Biosensors for Cell Monitoring

Song,

Hwang,

Jeon

et al. 2024

IJMS

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Sensing volatile organic compounds with CVD graphene: insights from quartz crystal microbalance and surface plasmon resonance studies

Selvi,

Capan,

Capan

et al. 2024

J Mater Sci: Mater Electron

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This study explores the sensing capabilities of chemical vapor deposition (CVD)-grown graphene in detecting volatile organic compounds (VOCs) through quartz crystal microbalance (QCM) and surface plasmon resonance (SPR) techniques. Two distinct sensing devices were developed, each tailored for QCM and SPR transducing mechanisms, utilizing CVD graphene as the sensing element. The sensors demonstrated consistent and reproducible responses when exposed to various concentrations of dichloromethane, chloroform, carbon tetrachloride, benzene, toluene, and m-xylene. Notably, both sensors exhibited unparalleled sensitivity to dichloromethane, with the graphene-coated SPR sensor displaying a sensitivity value of 294 × 10−3 ppm−1 and a limit of detection (LOD) value of 10.62 ppm. Additionally, the SPR sensor showcased remarkably swift response and recovery times, both under 3 sec. Results indicate that the adsorption of VOC molecules on the CVD graphene surface increases with the rising dipole moments and vapor pressure values of the molecules. The utilization of CVD graphene in both sensing approaches demonstrates good reproducibility in detecting ultralow concentrations of VOCs at room temperature.

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Developing an ultra-sensitive biosensor utilizing one-dimensional photonic crystal for anemia diagnosis

Chakraborty,

Ghosh,

Chatterjee

et al. 2024

J Opt

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Optical sensors of volatile organic compounds for non-invasive diagnosis of diseases

Cited by 8 publications

References 112 publications

The Biomedical Applications of Biomolecule Integrated Biosensors for Cell Monitoring

The Biomedical Applications of Biomolecule Integrated Biosensors for Cell Monitoring

Sensing volatile organic compounds with CVD graphene: insights from quartz crystal microbalance and surface plasmon resonance studies

Developing an ultra-sensitive biosensor utilizing one-dimensional photonic crystal for anemia diagnosis

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