Optical nanosensors for cancer and virus detections

Farmani, Ali; Soroosh, Mohammad; Mozaffari, Mohammad Hazhir; Daghooghi, Tina

doi:10.1016/b978-0-12-819870-4.00024-4

Cited by 40 publications

(13 citation statements)

References 47 publications

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“…Furthermore, the combination of nanomaterials with microfluidics and modern optical sensing techniques has led to the emergence of a novel and rapidly growing interdisciplinary research field, namely optofluidics [ 65 , 66 ], which has significantly increased detection sensitivity and reduced the detection limit for various biosensors [ 67 ]. The surface-enhanced Raman spectroscopy (SERS) is an ideal example of a detection method that has considerably benefitted from the integration of optical nanosensors within microfluidic devices [ 68 , 69 ].…”

Section: Design and Working Principlesmentioning

confidence: 99%

Biosensors-on-Chip: An Up-to-Date Review

et al. 2020

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Generally, biosensors are designed to translate physical, chemical, or biological events into measurable signals, thus offering qualitative and/or quantitative information regarding the target analytes. While the biosensor field has received considerable scientific interest, integrating this technology with microfluidics could further bring significant improvements in terms of sensitivity and specificity, resolution, automation, throughput, reproducibility, reliability, and accuracy. In this manner, biosensors-on-chip (BoC) could represent the bridging gap between diagnostics in central laboratories and diagnostics at the patient bedside, bringing substantial advancements in point-of-care (PoC) diagnostic applications. In this context, the aim of this manuscript is to provide an up-to-date overview of BoC system development and their most recent application towards the diagnosis of cancer, infectious diseases, and neurodegenerative disorders.

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Section: Design and Working Principlesmentioning

confidence: 99%

Biosensors-on-Chip: An Up-to-Date Review

et al. 2020

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“…Thus, they are more popular among designers. A large number of parameters, including the radius of the dielectric rod, the lattice constant, the type of rod arrangement, the dielectric constant, and the PhC unit cells' position, affect the resonant's intensity and frequency modes [14][15][16][17][18][19]. By changing every parameter, the blue or redshift occurs at resonant modes.…”

Section: Introductionmentioning

confidence: 99%

A novel design of fast and compact all-optical full-adder using nonlinear resonant cavities

Naghizade

Saghaei

2021

Opt Quant Electron

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In this paper, we report a new design of all-optical full-adder using two nonlinear resonators. The PhCbased full-adder consists of three input ports (A, B, and C for input bits), two nonlinear resonant cavities, several waveguides, and two output ports (for the Sum and Carry). Eight silicon rods and a nonlinear rod composed of doped glass form each resonant cavity. The well-known plane wave expansion technique is used to calculate the photonic band structure. It shows a wide photonic bandgap in the wavelength range of 1365 nm to 2074 nm covering the C and L optical transmission bands. The nite-difference timedomain method is applied to study the light propagation inside the full-adder. Our numerical results demonstrate when the incoming light intensity increases, the nonlinear optical Kerr effect appears and controls the direction of light emitted inside the structure as desired. The maximum time delay and footprint of the proposed full-adder are about 3ps and 758.5 µm 2 , respectively. Therefore, due to the low time delay and small footprint, the presented design can be used as a basic mathematical operator in the all-optical arithmetic logic unit.

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“…Performance of SPR is based on changing of refractive index in different synthesis. It is noteworthy when plasmon is generated by incident wavelength in specific ranges and angles they can be used in different detection [34,35]. The smart detection based on surface plasmon resonance has demonstrated ultra-sensitive qualification in biomolecules sensing by converting small changes in refractive index into spectral changes.…”

Section: Introductionmentioning

confidence: 99%

“…Localized surface plasmon resonance (LSPR) also is considerable biosensor for biological detection. The main principle mechanism of detection is based on interaction between incident light and analytic sample resulting in generating optical signal that record by detector [34,35,39,40]. Bio sensing application is impacted by surface parameter and physical and chemical properties (roughness, valence and conductance band, concentration of sample, functional group).…”

Section: Introductionmentioning

confidence: 99%

Monitoring Biomaterials with Light: Review of Surface Plasmon Resonance Biosensing Using two Dimensional Materials

Yari¹,

Farmani²,

Farmani³

et al. 2021

Preprint

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The purpose of this paper is to present advanced techniques in optical biodevices. Moreover different configurations involving the generation of fiber optical biosensors are described. To overcome some limitations of fiber optical biosensors, plasmonic phenomena proposed. In addition novel plasmonic phenomena have broaden researcher’s horizons in new discovering in terms of technology and application. As regards there are many challenges to detect ultra-low concentration samples with high sensitivity in real time. Researchers have always made great efforts to discover more effective methods. Throughout the paper SPR and LSPR as a powerful analysis instrument are introduced. Finally surveys the current practical performances of plasmonic sensors in detection of bio target are provided. As a result these devices demonstrate great potential in identifying target analytic due to their unique optical biosensors.

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Optical nanosensors for cancer and virus detections

Cited by 40 publications

References 47 publications

Biosensors-on-Chip: An Up-to-Date Review

Biosensors-on-Chip: An Up-to-Date Review

A novel design of fast and compact all-optical full-adder using nonlinear resonant cavities

Monitoring Biomaterials with Light: Review of Surface Plasmon Resonance Biosensing Using two Dimensional Materials

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