Optical memory effect of excised cataractous human crystalline lenses

Abstract

Cataracts increase the amount of scattered light in the crystalline lens producing low-contrast retinal images and causing vision impairment. The Optical Memory Effect is a wave correlation of coherent fields, which can enable imaging through scattering media. In this work, we characterize the scattering properties of excised human crystalline lenses by measuring their optical memory effect and other objective scattering parameters, finding the relationship between them. This work has the potential to help fundus imaging techniques through cataracts as well as the non-invasive correction of vision through cataracts.

Wavefront shaping and optical memory effect in ex-vivo cataractous crystalline lenses

“…WS is based on the coherent control of the wavefront incident on a scattering medium, using a spatial light modulator for the local manipulation of the phase and/or amplitude of the wavefront. Recently wavefront shaping techniques have been suggested for the optical (non-surgical) correction of scattering in cataractous lenses 2 aided by the Optical Memory Effect, in order to predict the optimal isoplanatic patch of the potential optimized image 3 . In this work we perform wavefront shaping optimizations on human cataractous crystalline lenses for the first time, measuring their Optical Memory Effect before and after the wavefront optimization has been performed, which allows us to perform a more rigorous prediction regarding the optimized image isoplanatic path.…”