Optical discrimination of racemic from achiral solutions

Steinbacher, Andreas; Nuernberger, Patrick; Brixner, Tobias

doi:10.1039/c4cp05641h

Cited by 7 publications

(6 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The related studies of gas phase chiral molecules focus on the measurements of enantiomeric excess, handedness of a given compound, and on devising techniques for manipulating mixtures containing both enantiomers [3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21]. In addition, over the years more ambitious directions were considered theoretically -laser assisted asymmetric synthesis, enantiomeric interconversion and purification (e.g.…”

Section: Introductionmentioning

confidence: 99%

Laser-induced persistent orientation of chiral molecules

et al. 2019

View full text Add to dashboard Cite

We show, both classically and quantum mechanically, enantioselective orientation of gas phase chiral molecules excited by laser fields with twisted polarization. Counterintuitively, the induced orientation, whose direction is laser controllable, does not disappear after the excitation, but stays approximately constant long after the end of the laser pulses, behavior unique to chiral systems. We computationally demonstrate this long-lasting orientation using propylene oxide molecules (CH3CHCH2O, or PPO) as an example, and consider two kinds of fields with twisted polarization: a pair of delayed cross-polarized pulses, and an optical centrifuge. This novel chiral effect opens new avenues for detecting molecular chirality, measuring enantiomeric excess and separating enantiomers with the help of inhomogeneous external fields.

show abstract

Section: Introductionmentioning

confidence: 99%

Laser-induced persistent orientation of chiral molecules

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Laser pulse shaping not only lifts the constraint of having separate pulse beams in non-linear spectroscopy and microscopy [243][244][245], it also addresses naturally the requirement to decipher the interference which is at the basis of the non-linear spectroscopies. Eventually, this understanding has lead to the use of laser pulse shaping in optical imaging with compensation of the effect of scattering media such as biological tissue [249,250]; optical microscopy with enhanced chemical sensitivity and contrast [251][252][253][254]; chemical analysis and detection via optical discrimination [255][256][257][258]; cancer diagnosis [259]; and material processing [260]. Similarly, laser pulse shaping is expected to enhance chemical sensitivity in other detection methods such as mass spectroscopy [261,262].…”

Section: State Of the Artmentioning

confidence: 99%

Training Schrödinger’s cat: quantum optimal control

et al. 2015

View full text Add to dashboard Cite

Abstract. It is control that turns scientific knowledge into useful technology: in physics and engineering it provides a systematic way for driving a dynamical system from a given initial state into a desired target state with minimized expenditure of energy and resources. As one of the cornerstones for enabling quantum technologies, optimal quantum control keeps evolving and expanding into areas as diverse as quantumenhanced sensing, manipulation of single spins, photons, or atoms, optical spectroscopy, photochemistry, magnetic resonance (spectroscopy as well as medical imaging), quantum information processing and quantum simulation. In this communication, state-of-the-art quantum control techniques are reviewed and put into perspective by a consortium of experts in optimal control theory and applications to spectroscopy, imaging, as well as quantum dynamics of closed and open systems. We address key challenges and sketch a roadmap for future developments. ForewordThe authors of this paper represent the QUAINT consortium, a European Coordination Action on Optimal Control of Quantum Systems, funded by the European Commission Framework Programme 7, Future Emerging Technologies FET-OPEN programme and the Virtual Facility for Quantum Control (VF-QC). This consortium has considerable expertise in optimal control theory and its applications to quantum systems, both in existing areas, such as spectroscopy and imaging, and in emerging quantum technologies, such as quantum information processing, quantum communication, quantum simulation a e-mail: fwm@lusi.uni-sb.de and quantum sensing. The list of challenges for quantum control has been gathered by a broad poll of leading researchers across the communities of general and mathematical control theory, atomic, molecular-, and chemical physics, electron and nuclear magnetic resonance spectroscopy, as well as medical imaging, quantum information, communication and simulation. 144 experts in these fields have provided feedback and specific input on the state of the art, mid-term and long-term goals. Those have been summarized in this document, which can be viewed as a perspectives paper, providing a roadmap for the future development of quantum control. Because such an endeavour can hardly ever be complete (there are many additional areas of quantum control applications, such as spintronics, nano-optomechanical technologies etc.), this roadmap

show abstract

“…Methods for chiral discrimination based on electric-dipole interactions have been shown to produce much higher chiral signals. Those include various versions of photo-electron circular dichroism [18][19][20][21][22][23][24][25] (including multiphoton and strong-field ionization regimes [26][27][28][29][30] as well as high harmonic generation [31]), Coulomb explosion imaging [7,8,[32][33][34], and enantiosensitive microwave spectroscopy [5,6]. A unified analysis of this new class of chiral measurements without magnetic interactions can be found in Ref.…”

mentioning

confidence: 99%

Controlled Enantioselective Orientation of Chiral Molecules with an Optical Centrifuge

et al. 2019

View full text Add to dashboard Cite

We report on the first experimental demonstration of enantioselective rotational control of chiral molecules with a laser field. In our experiments, two enantiomers of propylene oxide are brought to accelerated unidirectional rotation by means of an optical centrifuge. Using Coulomb explosion imaging, we show that the centrifuged molecules acquire preferential orientation perpendicular to the plane of rotation, and that the direction of this orientation depends on the relative handedness of the enantiomer and the rotating centrifuge field. The observed effect is in agreement with theoretical predictions and is reproduced in numerical simulations of the centrifuge excitation followed by Coulomb explosion of the centrifuged molecules. The demonstrated technique opens new avenues in optical enantioselective control of chiral molecules with a plethora of potential applications in differentiation, separation and purification of chiral mixtures.

show abstract

Optical discrimination of racemic from achiral solutions

Cited by 7 publications

References 50 publications

Laser-induced persistent orientation of chiral molecules

Laser-induced persistent orientation of chiral molecules

Training Schrödinger’s cat: quantum optimal control

Controlled Enantioselective Orientation of Chiral Molecules with an Optical Centrifuge

Contact Info

Product

Resources

About