Optical diagnosis of testicular torsion: feasibility and methodology

Shadgan, Babak; Macnab, Andrew; Stothers, Lynn; Kajbafzadeh, Abdol‐Mohammad

doi:10.1117/12.2038283

Cited by 5 publications

(13 citation statements)

References 17 publications

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“…The remaining 17 articles where fully reviewed. Nine articles were finally selected for inclusion in the systematic review after excluding a further eight irrelevant articles (Fig. ).…”

Section: Resultsmentioning

confidence: 99%

“…Five of the studies had human participants . The four animal studies used sheep, and rabbits and rats …”

Section: Resultsmentioning

confidence: 99%

“…None of the studies enrolled subjects over the age of 30 years. The age range of subjects in the five human studies were 14 months, 14–74 months, 1 month to <18 years, 16–29 years and <30 years …”

Section: Resultsmentioning

confidence: 99%

“…Of the 253 participants, TT was confirmed in 122 (67 animals and 55 humans). The largest study had 121 participants whilst the smallest included manuscript had one subject . The mean sample size of all included studies was 28.1 (standard deviation 40.8).…”

Section: Resultsmentioning

confidence: 99%

“…Amongst the five human‐based studies, two were conducted in the USA, whilst one study was conducted in USA and Turkey . The remaining two studies did not specify the study site …”

Section: Resultsmentioning

confidence: 99%

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Near‐infrared spectroscopy in the diagnosis of testicular torsion: valuable modality or waste of valuable time? A systematic review

Laher

Swart

Honiball

et al. 2019

ANZ Journal of Surgery

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Background: Testicular torsion (TT) is a urological emergency that affects one in 4000 males younger than 25 years. Delays in the management of TT may result in testicular ischaemia, testicular necrosis, orchidectomy and infertility. This review assesses the validity of near-infrared spectroscopy (NIRS) as a diagnostic tool in the assessment and diagnosis of TT. Methods: A systematic search of Cochrane Database of Systematic Reviews, EMBASE, Google Scholar, PubMed, Scopus and Web of Science databases was performed in January 2019 using specific search terms. Selected studies were ranked and evaluated using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and the Quality Assessment of Diagnostic Accuracy Studies-2 tool. Results: A total of nine studies that included 253 subjects (88 animals and 165 humans) with a mean sample size of 28.1 (standard deviation 40.8) subjects were included. The mean difference in testicular tissue oxygen saturation between torsed and non-torsed testes (Δ%StO 2 ) were 45%, 42% (AE5%), 26% and 5-18% in four animal studies and 2.0%, 3.0%, 6.7%, 6.8% and 23.0% in five human studies. The tissue oxygen saturation difference between contralateral healthy testes (controls) ranged from 1% to 10% in the five studies that alluded to this. Conclusion: The current body of evidence does not support the use of NIRS in the workup of TT. Well-designed clinical trials with large patient samples are required to determine whether NIRS may have some future role as a diagnostic modality in TT.© 2019 Royal Australasian College of Surgeons ANZ J Surg 90 (2020) 708-714ANZJSurg.com

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“…The remaining 17 articles where fully reviewed. Nine articles were finally selected for inclusion in the systematic review after excluding a further eight irrelevant articles (Fig. ).…”

Section: Resultsmentioning

confidence: 99%

“…Five of the studies had human participants . The four animal studies used sheep, and rabbits and rats …”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

“…Amongst the five human‐based studies, two were conducted in the USA, whilst one study was conducted in USA and Turkey . The remaining two studies did not specify the study site …”

Section: Resultsmentioning

confidence: 99%

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