Abstract:The interaction between actin and myosin II plays an important role in a variety of cellular functions. In particular, myosin II is involved in muscle contraction, which is attributed to the sliding of thin filament actin past the thick myosin II filaments. Past studies on the structure of myosin have linked severe pathologies to defects in myosin, making it important to understand the mechanism of the system. In this study, we focus our analysis on the powerstroke of the myosin II cross bridge cycle, which is… Show more
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