Optical Coherence Tomography Thickness Measurements of the Extraocular Rectus Muscle Tendons in Graves' Ophthalmopathy

De‐Pablo‐Gómez‐de‐Liaño, Lucía; Fernández‐Vigo, José Ignacio; Ventura-Abreu, Néstor; Troyano-Rivas, J.A.; Niño-Rueda, Cristina; Romo-López, Á.; Gómez-de-Liaño, R.

doi:10.3928/01913913-20180802-01

Cited by 9 publications

(5 citation statements)

References 28 publications

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“…ОКТ переднего сегмента с расширенной глубиной визуализации (EDI AS-OCT) при ЭОП показало, что увеличение толщины сухожилий медиальной и латеральной прямых экстраокулярных мышц (ЭОМ) хорошо определяется и коррелирует с параметрами магниторезонансной томографии (МРТ) [21,41,42]. N. H ner и соавт.…”

Section: Optical Coherence Tomography and Optical Coherence Tomograph...unclassified

“…L. De-Pablo-G mez-de-Lia o и соавт. [42] выявили наличие корреляции между толщиной сухожилий латеральной и медиальной прямых ЭОМ (EDI AS-OCT) и CAS ЭОП. С точки зрения авторов, исследование толщины сухожилия медиальной прямой мышцы с использованием EDI AS-OCT может проводиться с целью мониторинга пациентов с ЭОП.…”

Section: Optical Coherence Tomography and Optical Coherence Tomograph...unclassified

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Optical coherence tomography and optical coherence tomography — angiography used in endocrine ophthalmopathy

Gavrilova¹,

Kutrovskaya²,

Salimova³

2023

Rossijskij oftalʹmologičeskij žurnal

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The literature review presents the results of optical coherence tomography and optical coherence tomography — angiography used for Graves’ orbitopathy. The data on the thickness of the inner layers of the retina, microcirculation in the peripapillary and macular regions, parameters of the choroid, lamina cribrosa and extraocular muscles were analyzed as possible diagnostic criteria of the condition.

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Section: Optical Coherence Tomography and Optical Coherence Tomograph...unclassified

Optical coherence tomography and optical coherence tomography — angiography used in endocrine ophthalmopathy

Gavrilova¹,

Kutrovskaya²,

Salimova³

2023

Rossijskij oftalʹmologičeskij žurnal

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“…Of now, a cumulative dose of 4.5-5 g of intravenous methylprednisolone is recommended for moderate-tosevere TED. 71 Kahaly et al recommended dose of IV methylprednisolone (500 mg weekly x 6 week then 250 mg weekly x 6 weeks for a total dose of 4.5g ) for TED. 72 Besides this, steroid-sparing agents like cyclosporine and MMF have also been shown to be effective in TED treatment in study conducted at Cambridge namely close endocrine control and it was observed that the early introduction of cyclosporin after initial systemic glucocorticoid immunosuppression has resulted in a 7-fold reduction in decompression surgery.…”

Section: Immunosuppressive Therapymentioning

confidence: 99%

Recent advances in thyroid eye disease: An overview

Maurya¹,

Ananya

Kadir³

et al. 2021

IJOOO

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Thyroid eye disease (TED) is a chronic debilitating condition which causes physical discomfort, oculo-facial disfigurement and compromised visual function. Around 25% of people with Graves’ hyperthyroidism are affected by TED, where 1 in 20 patients might report with moderate-to-severe, active disease that will require medical management for reducing both TED activity and severity. The mainstay of medical management involves intravenous corticosteroids for active moderate-to-severe TED. After accurate understanding of the mechanism and pathophysiology of this disease, investigations and randomized clinical trials have been conducted. The role of immunotherapy targeting and influencing different biomolecular pathways including that of T cells, B cells, cytokines and cell surface receptors have been investigated in various randomized clinical trials. This review article addresses the epidemiology, associated risk factors, recent advances in pathophysiology, newer diagnostic tools and current management options available for TED which include the use of immunosuppressive drugs like rituximab (RTX), tocilizumab, infliximab (IFX), etanercept ( ETN) and teprotumumab etc.

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“…Optical coherence tomography (OCT) is a rapid, noninvasive, and readily available imaging modality which has become a standard of care for evaluating retina disease. Recent studies have shown that OCT is an accurate method for measuring horizontal rectus tendons, which can differentiate TED from normal eyes [8]. With the advent of swept-source OCT (SS-OCT), enhanced light penetration through the retinal pigment epithelium (RPE) enables more effective visualization of the choroidal and scleral layers [9,10].…”

Section: Introductionmentioning

confidence: 99%

Quantitative analysis of choroidal alterations in thyroid eye disease using swept-source OCT

et al. 2023

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Purpose: To investigate choroidal alterations in patients with thyroid eye disease (TED) using swept-source optical coherence tomography (SS-OCT) and compare them with age-matched healthy controls.Methods: SS-OCT scans were performed to obtain quantitative measurements of choroidal parameters. Mean choroidal thickness (MCT), choroidal vessel volume (CVV), choroidal stroma volume (CSV), choroidal vascularity index (CVI), and choroidal stroma-to-vessel volume ratio (CSVR) were calculated and compared between TED and control eyes.Results: TED eyes exhibited significantly higher MCT (276.25 ± 58.75 μm vs. 236.86 ± 45.02 μm, p < 0.001), CVV (21.46 ± 5.10 mm3vs. 18.14 ± 3.83 mm3, p = 0.001), and CSV (13.86 ± 2.80 mm3vs. 11.44 ± 2.17 mm3, p < 0.001) compared to control eyes. However, there were no significant differences in CVI (0.61 ± 0.02 vs. 0.61 ± 0.03, p = 0.838) or CSVR (0.65 ± 0.05 vs. 0.64 ± 0.07, p = 0.345) between the two groups.Conclusion: SS-OCT effectively differentiated TED eyes from normal eyes based on choroidal alterations. The increased MCT, CVV, and CSV in TED suggest both dilated choroidal vasculature and expanded choroidal stroma. These findings highlight the potential of SS-OCT as an adjunctive imaging tool for the assessment of TED.

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Optical Coherence Tomography Thickness Measurements of the Extraocular Rectus Muscle Tendons in Graves' Ophthalmopathy

Cited by 9 publications

References 28 publications

Optical coherence tomography and optical coherence tomography — angiography used in endocrine ophthalmopathy

Optical coherence tomography and optical coherence tomography — angiography used in endocrine ophthalmopathy

Recent advances in thyroid eye disease: An overview

Quantitative analysis of choroidal alterations in thyroid eye disease using swept-source OCT

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