Optical coherence tomography - principles and applications

Abstract

We consider the use of single-photon counting detectors in coherence-domain imaging. Detectors operated in this mode exhibit reduced noise, which leads to increased sensitivity for weak light sources and weakly reflecting samples. In particular, we experimentally demonstrate the possibility of using superconducting single-photon detectors (SSPDs) for optical coherence-domain reflectometry (OCDR). These detectors are sensitive over the full spectral range that is useful for carrying out such imaging in biological samples. With counting rates as high as 100 MHz, SSPDs also offer a high rate of data acquisition if the light flux is sufficient.

Intra-retinal Layer Segmentation in Optical Coherence Tomography Using an Active Contour Approach

“…The resolution in OCT systems approaches that of histology; the lateral resolution is typically 10-20μm and the axial resolution is typically ∼4μm [1].…”

Examination of Sol-Gel Derived Hydroxyapatite Enhanced with Silver Nanoparticles using OCT and Raman Spectroscopy

“…The optical coherence tomography (OCT), which has been used in this study to examine distribution of silver nanoparticles inside the hydroxyapatite colloids, is a contact-free, noninvasive measurement technique widely known for its biomedical applications, especially in ophthalmology [17]. It has also proven to be useful in evaluation of technical objects and recent research results have shown its potential for nanocomposite material inspection [18−19].…”

1550 nm superluminescent diode and anti-Stokes effect CCD camera based optical coherence tomography for full-field optical metrology

“…Assuming polarization effects are negligible, the mathematical treatment of the LCI signal [7] is started with the Fourier Transform (FT) representation of the electric field E(t):…”