Optical Coherence Tomography of Optic Disk Melanocytoma in 15 Cases

Abstract

Optic disk melanocytoma shows characteristic features by OCT including a gradual transition from normal retina into nodular tumor, and the mass displays a bright anterior border layer with optically empty internal details.

Autofluorescence and spectral-domain optical coherence tomography of optic disk melanocytoma

“…Despite the characteristic clinical appearance of melanocytoma, conditions such as primary or metastatic choroidal melanoma and combined hamartoma of the retina and RPE must first be ruled out (1,3,4) . Other differential diagnoses include choroidal nevus, RPE hy perplasia, and RPE adenoma (1,4) .…”

“…Other differential diagnoses include choroidal nevus, RPE hy perplasia, and RPE adenoma (1,4) . Transformation of melanocytoma into malignant melanoma is extremely rare (6) .…”

“…OCT is a valuable tool for examining the retina and inner choroid architecture (7) . OCT patterns and applications are well described in several choroidal and retinal tumors (4,7) . OCT findings in ODM include sloped and brightly reflective anterior tumor surface, adjacent retinal disorganization, and abrupt posterior optical shadowing (3) .…”

“…OCT findings in ODM include sloped and brightly reflective anterior tumor surface, adjacent retinal disorganization, and abrupt posterior optical shadowing (3) . Vitreous seeds can be found (4) . Both of the presented cases showed the characteristic features.…”

“…It can be defined as a melanocytic nevus variant located at the optic disk and histopathologically presents as uniform, deeply pigmented cells with melanosomes and after bleaching, small uniform nuclei with inconspicuous nucleo li and abundant cytoplasm (2) . ODM is usually diagnosed by ophthalmoscopic examination due to the characteristic appearance of the tumor (1,3,4) . Ancillary procedures, such as fundus photography, fluorescein angiography (FA), and optical coherence tomography (OCT), can help the diagnosis and are useful for follow-up evaluations (1) .…”