2011
DOI: 10.1007/s12551-011-0054-7
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Optical coherence tomography: fundamental principles, instrumental designs and biomedical applications

Abstract: The advances made in the last two decades in interference technologies, optical instrumentation, catheter technology, optical detectors, speed of data acquisition and processing as well as light sources have facilitated the transformation of optical coherence tomography from an optical method used mainly in research laboratories into a valuable tool applied in various areas of medicine and health sciences. This review paper highlights the place occupied by optical coherence tomography in relation to other imag… Show more

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Cited by 162 publications
(108 citation statements)
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References 103 publications
(98 reference statements)
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“…OCT is based on interferometry in so-called weakly coherent (i.e., polychromatic or white) light. There are different variants of OCT, all of them typically use Michelson interferometers [182]. Full-field OCT utilizes a Michelson interferometer with microscope lenses placed in both arms [13,54].…”
Section: Optical Coherence Tomographymentioning
confidence: 99%
“…OCT is based on interferometry in so-called weakly coherent (i.e., polychromatic or white) light. There are different variants of OCT, all of them typically use Michelson interferometers [182]. Full-field OCT utilizes a Michelson interferometer with microscope lenses placed in both arms [13,54].…”
Section: Optical Coherence Tomographymentioning
confidence: 99%
“…It has better resolution than ultrasound and achieves deeper penetration than confocal microscopy, and it can provide distinctive morphological information over larger tissue regions than nonlinear optical microscopy. [82][83][84] Thus, OCT has been evaluated for the identification of characteristic architectural changes that correlate with the histological phases of cutaneous wound healing. 85,86 OCT is a low coherence light interferencebased technique.…”
Section: Vascular Mapping and Perfusion Measurements With Optical Cohmentioning
confidence: 99%
“…Based on a conventional TD-OCT, the MR-OCT signal at the output of an interferometer can be deduced. The detected signal signal I d (k)for TD-OCT [24] is stated in Eq. (2).…”
Section: Dermascope Integrated Mr-oct Systemmentioning
confidence: 99%