Optical Coherence Tomography for the Middle and Inner Ear

Ilgner, Justus; Just, Tino; Farkas, C; Lenenbach, Achim; Westhofen, Martin

doi:10.1007/978-1-4939-1758-7_33

Cited by 1 publication

(2 citation statements)

References 17 publications

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“…OCT is a key research tool in experimental ME and hearing research, as researchers can remove the external auditory canal (EAC) to closer image the TM and view its medial side 48 . Using OCT to characterize the thickness distribution of the ex vivo TM has assisted hearing researchers in creating better mathematical and finite element models of ME biomechanics and has a role to play in surgical prosthesis and graft modeling 49,50 .…”

Section: Discussionmentioning

confidence: 99%

“…OCT is a key research tool in experimental ME and hearing research, as researchers can remove the external auditory canal (EAC) to closer image the TM and view its medial side. 48 Using OCT to characterize the thickness distribution of the ex vivo TM has assisted hearing researchers in creating better mathematical and finite element models of ME biomechanics and has a role to play in surgical prosthesis and graft modeling. 49,50 As an imaging tool, OCT has been used as a tool to assess the healing of experimental grafts in mouse models 51 and, in another study, to assess the ''fit'' and placement of a film patch (with an integrated strain gauge that was used to detect TM movement) on a normal TM.…”

Section: Oct Imaging As a Research Toolmentioning

confidence: 99%

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Optical Coherence Tomography of the Tympanic Membrane and Middle Ear: A Review

Tan

Maria

Wijesinghe

et al. 2018

Otolaryngol.--head neck surg.

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Objective To evaluate the recent developments in optical coherence tomography (OCT) for tympanic membrane (TM) and middle ear (ME) imaging and to identify what further development is required for the technology to be integrated into common clinical use. Data Sources PubMed, Embase, Google Scholar, Scopus, and Web of Science. Review Methods A comprehensive literature search was performed for English language articles published from January 1966 to January 2018 with the keywords "tympanic membrane or middle ear,""optical coherence tomography," and "imaging." Conclusion Conventional imaging techniques cannot adequately resolve the microscale features of TM and ME, sometimes necessitating diagnostic exploratory surgery in challenging otologic pathology. As a high-resolution noninvasive imaging technique, OCT offers promise as a diagnostic aid for otologic conditions, such as otitis media, cholesteatoma, and conductive hearing loss. Using OCT vibrometry to image the nanoscale vibrations of the TM and ME as they conduct acoustic waves may detect the location of ossicular chain dysfunction and differentiate between stapes fixation and incus-stapes discontinuity. The capacity of OCT to image depth and thickness at high resolution allows 3-dimensional volumetric reconstruction of the ME and has potential use for reconstructive tympanoplasty planning and the follow-up of ossicular prostheses. Implications for Practice To achieve common clinical use beyond these initial discoveries, future in vivo imaging devices must feature low-cost probe or endoscopic designs and faster imaging speeds and demonstrate superior diagnostic utility to computed tomography and magnetic resonance imaging. While such technology has been available for OCT, its translation requires focused development through a close collaboration between engineers and clinicians.

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Section: Discussionmentioning

confidence: 99%