Optical coherence tomography as an accurate inspection and quality evaluation technique in paper industry

Prykäri, Tuukka; Czajkowski, Jakub; Alarousu, Erkki; Myllylä, Risto

doi:10.1007/s10043-010-0039-y

Cited by 47 publications

(21 citation statements)

References 11 publications

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“…To date, applications of OCT beyond biomedicine have been scarce. Nevertheless, there have been some reports on using OCT for the non-destructive evaluation of thickness of papers [11], and surface roughness, gloss and bulk properties of flat-faced tablets [12]. Very recently, OCT has also been evaluated for characterizing the coating thickness of pharmaceutical tablets [13] and for imaging pharmaceutical tablets [14].…”

Section: Introductionmentioning

confidence: 98%

Non-destructive quantification of pharmaceutical tablet coatings using terahertz pulsed imaging and optical coherence tomography

Zhong¹,

Shen

et al. 2011

Optics and Lasers in Engineering

122

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Optical coherence tomography (OCT) and terahertz pulsed imaging (TPI) are two powerful techniques allowing high quality cross-sectional images from within scattering media to be obtained non-destructively. In this paper, we report experimental results of using OCT and TPI for quantitatively characterizing pharmaceutical tablet coatings in the thickness range of 10–140 μm. We found that the spectral OCT system developed in-house has an axial resolution of 0.9 μm, and is capable of quantifying very thin coatings in the range of 10–60 μm. The upper limit of 60 μm within the tablet coating and core is owed to the strong scattering of OCT light, which has relatively short wavelengths in the range of 0.5–1.0 μm. On the other hand, TPI utilizes terahertz radiation that has substantially long wavelengths in the range of hundreds of microns, and thus is less prone to the scattering problem. Consequently TPI has been demonstrated to be able to quantify thicker coatings in the range of 40–140 μm and beyond. We concluded that OCT and TPI are two complementary analytical techniques for non-destructive and quantitative characterization of pharmaceutical tablet coatings

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Section: Introductionmentioning

confidence: 98%

Non-destructive quantification of pharmaceutical tablet coatings using terahertz pulsed imaging and optical coherence tomography

Zhong¹,

Shen

et al. 2011

Optics and Lasers in Engineering

122

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show abstract

“…As we stated in our previous publications, 15,17 optical coherence tomography grown up to be mature technique. The state of the art Fourier domain OCT (FD-OCT) systems are capable of providing both high axial measurement resolution and very high, video-rate data acquisition speed.…”

Section: Resultsmentioning

confidence: 97%

Evaluation of microfluidic channels with optical coherence tomography

et al. 2010

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Application of time domain, ultra high resolution optical coherence tomography (UHR-OCT) in evaluation of microfluidic channels is demonstrated. Presented study was done using experimental UHR-OCT device based on a Kerr-lens mode locked Ti:sapphire femtosecond laser, a photonic crystal fibre and modified, free-space Michelson interferometer. To show potential of the technique, microfluidic chip fabricated by VTT Center for Printed Intelligence (Oulu, Finland) was measured. Ability for full volumetric reconstruction in non-contact manner enabled complete characterization of closed entity of a microfluidic channel without contamination and harm for the sample. Measurement, occurring problems, and methods of postprocessing for raw data are described. Results present completely resolved physical structure of the channel, its spatial dimensions, draft angles and evaluation of lamination quality.

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“…The value quoted is typical of a measurement during the day on a lab bench without the use of special anti-vibration devices. Recently, Prykäri et al [27] used an ultra-high resolution (submicron axial resolution) TD OCT to measure the topography of glossy paper. By measuring the highest intensity point on a highly sampled interferogram, a 1σ 8 accuracy of 60nm for the surface profile was quoted, which we have shown to be possible with a much lower resolution OCT without the need to develop expensive ultra-high resolution OCT.…”

Section: Smooth Surface Performancementioning

confidence: 99%

High precision dynamic multi-interface profilometry with optical coherence tomography

Lawman

Liang

2011

Appl. Opt.

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Optical coherence tomography as an accurate inspection and quality evaluation technique in paper industry

Cited by 47 publications

References 11 publications

Non-destructive quantification of pharmaceutical tablet coatings using terahertz pulsed imaging and optical coherence tomography

Non-destructive quantification of pharmaceutical tablet coatings using terahertz pulsed imaging and optical coherence tomography

Evaluation of microfluidic channels with optical coherence tomography

High precision dynamic multi-interface profilometry with optical coherence tomography

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