Optical coherence tomography angiography (OCTA) findings in juvenile idiopathic arthritis

Elnahry, Ayman G.; Hassan, Lameece Moustafa; Abdelrahman, Walaa; Elmohsen, Mai Nasser Abd

doi:10.1016/j.ejr.2022.11.010

Cited by 1 publication

(1 citation statement)

References 25 publications

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“…Quantitative OCTA showed significantly decreased SCP and DCP vessel density in eyes with pediatric uveitis, regardless of disease activity [ 163 ]. Similar findings were also shown in JIA-related uveitis in 38 eyes from 20 Egyptian children (with a mean age of 10.7 ± 2.6 years); in moderate-to-severe-activity JIA-related uveitis patients, significantly lower VD in the SCP and DCP, increased FAZ and decreased central macular thickness were noted [ 164 ]. In active pediatric anterior uveitis, the subfoveal choroidal thickness (SFCT) was increased in comparison to inactive and control patients but the FAZ and central macular thickness (CMT) were not significantly different [ 163 ].…”

Section: Oct and Octa In Inflammatory/uveitic Diseasessupporting

confidence: 74%

Optical Coherence Tomography and Optical Coherence Tomography Angiography in Pediatric Retinal Diseases

et al. 2023

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Indirect ophthalmoscopy and handheld retinal imaging are the most common and traditional modalities for the evaluation and documentation of the pediatric fundus, especially for pre-verbal children. Optical coherence tomography (OCT) allows for in vivo visualization that resembles histology, and optical coherence tomography angiography (OCTA) allows for non-invasive depth-resolved imaging of the retinal vasculature. Both OCT and OCTA were extensively used and studied in adults, but not in children. The advent of prototype handheld OCT and OCTA have allowed for detailed imaging in younger infants and even neonates in the neonatal care intensive unit with retinopathy of prematurity (ROP). In this review, we discuss the use of OCTA and OCTA in various pediatric retinal diseases, including ROP, familial exudative vitreoretinopathy (FEVR), Coats disease and other less common diseases. For example, handheld portable OCT was shown to detect subclinical macular edema and incomplete foveal development in ROP, as well as subretinal exudation and fibrosis in Coats disease. Some challenges in the pediatric age group include the lack of a normative database and the difficulty in image registration for longitudinal comparison. We believe that technological improvements in the use of OCT and OCTA will improve our understanding and care of pediatric retina patients in the future.

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Section: Oct and Octa In Inflammatory/uveitic Diseasessupporting

confidence: 74%