Optical coherence tomography angiography for quantitative microvascular assessment in diabetic retinopathy: inter-device and intra-device agreement and correlation with clinical staging

Perivenular Capillary Rarefaction in Diabetic Retinopathy

“…In our study, high-speed acquisition alone (represented by Solix V1) and, even more, high-speed acquisition coupled with averaging technique (represented by Solix V4) brought to an underestimation of PD and a parallel overestimation of GPD, which is coherent with what was found in the literature in other courts of diabetic patients. 32 , 33 Nevertheless, we detected a good agreement between high-speed techniques and moderate agreement of both with standard acquisition (AngioVue). Our results confirmed what was previously found by Crincoli et al, 32 since the higher differences between zones were detected by Solix V1 in early stages and Solix V4 in advanced stages of the disease, and this is compatible with the optimized performances demonstrated for each of the 2 acquisition modes in early and advanced DR, respectively.…”

“… 32 , 33 Nevertheless, we detected a good agreement between high-speed techniques and moderate agreement of both with standard acquisition (AngioVue). Our results confirmed what was previously found by Crincoli et al, 32 since the higher differences between zones were detected by Solix V1 in early stages and Solix V4 in advanced stages of the disease, and this is compatible with the optimized performances demonstrated for each of the 2 acquisition modes in early and advanced DR, respectively.…”