“…Sensitivity and specificity have ranged from 83–100% and 84–100% using direct measurement of cerebrospinal fluid pressure or CT as a gold standard reference,15,16,33,34,36,37,39 but have been reported to be as low as 75% and 44%, respectively 35. In a recent meta-analysis of 12 studies including 478 adults and children, sensitivity and specificity for detecting CT findings associated with increased ICP were 95.6% and 92.3%, respectively 40.…”