Optic Edge Design as Long-term Factor for Posterior Capsular Opacification Rates

Kohnen, Thomas; Fabian, Ekkehard; Gerl, R; Hunold, W.; Hütz, Werner W.; Strobel, Jürgen; Hoyer, Heike; Mester, U

doi:10.1016/j.ophtha.2008.01.002

Cited by 89 publications

(80 citation statements)

References 51 publications

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“…Several studies also reported higher percentage of PCO in round optic edge (13.0%-38.7%) than square optic edge (1.4%-3.4%). [22][23][24] In conclusion, three years cumulative incidence of PCO in Cipto Mangunkusumo Hospital, Jakarta was 8.82%, with median time to PCO diagnosis of 21 months (1.75 years). There was no defined related factor to PCO reformation, but higher incidence of PCO was found in hydrophilic acrylic IOL than in hydrophobic acrylic IOL.…”

Section: Discussionmentioning

confidence: 75%

Incidence and associated factors of posterior capsule opacification in pseudophakic patients at Cipto Mangunkusumo Hospital

Ayuningtyas

Gondhowiardjo

2015

Med J Indones

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Background: Posterior capsule opacification (PCO) is the most common postoperative consequence of cataract surgery which may cause visual acuity reduction, yet the incidence in Indonesia has not been reported. The objectives of this study were to evaluate three years cumulative incidence of PCO and factors associated with PCO formation at Cipto Mangunkusumo Hospital, Jakarta.Methods: This was a retrospective descriptive study on patients with uneventful senile cataract surgery during year 2010. All related data were retrieved from medical records in year 2013, which included patient demographics, type of surgery, intraocular lens (IOL) characteristics (material, optic edge design and diameter). Moreover, time to first PCO diagnosis (month), and best corrected visual acuity (BCVA) pre-operatively, at time PCO was diagnosed and two weeks after Neodymium-doped yttrium aluminum garnet (Nd:YAG) laser were noted (decimal).Results: A total of 578 eyes (485 patients) were involved in this study. Three years cumulative incidence of the PCO was 8.82% (51 eyes). Phacoemulsification surgery was performed in 496 (85.8%) eyes. The median time to PCO diagnosis was 21 months (range 1 to 34 months), mean of BCVA was 0.50 ± 0.26. Age (<65 and >65 years old) was not associated to PCO. Higher incidence of PCO was found in patients using hydrophilic acrylic IOL (10.7%) than in hydrophobic acrylic (6.2%). After Nd:YAG laser was performed, BCVA was improved to 1.00.Conclusion: Three years cumulative incidence of PCO was 8.82% and there was no defined factor related to PCO formation, but higher percentage of PCO occured in patients using hydrophilic acrylic IOL than in hydrophobic acrylic.

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Section: Discussionmentioning

confidence: 75%

Incidence and associated factors of posterior capsule opacification in pseudophakic patients at Cipto Mangunkusumo Hospital

Ayuningtyas

Gondhowiardjo

2015

Med J Indones

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“…However, PCO remains one of the most common complications after cataract surgery. Numerous investigators have revealed three factors predominantly contributing to the incidence and degree of PCO: surgical technique, [8][9][10][11] IOL design, 12,13 and IOL material. In the present study, the same IOL SA60AT was implanted in all of the cases, indicating surgical procedure (technique) is only difference among the groups.…”

Section: Resultsmentioning

confidence: 99%

Posterior capsule opacification following 20- and 23-gauge phacovitrectomy (posterior capsule opacification following phacovitrectomy)

Iwase

Oveson

Nishi

2012

Eye

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Purpose To compare the development of posterior capsule opacification (PCO) for idiopathic epi-retinal membrane cases between 20-and 23-gauge phacovitrectomy. Methods Cataract surgery of phacoemulsification with the SA60AT implantation and 20-or 23-gauge vitrectomy was performed for 20 patients in both groups. Cataract surgery alone was performed for 50 patients as the control. The PCO density values were measured using Scheimpflug video photography at 1 week, 1, 3, 6, 12, 18, and 24 months after surgery. The number of eyes that required Nd:YAG laser capsulotomy was also examined. Results The mean PCO value in the 20-gauge phacovitrectomy group increased significantly with time (Po0.001), whereas those in the 23-gauge phacovitrectomy group and the cataract surgery group did not show any significant change. Furthermore, the PCO value in the 20-gauge phacovitrectomy group was significantly greater than that in the 23-gauge phacovitrectomy group at 6, 12, 18 (Po0.05), and 24 months (Po0.01) after surgery. The PCO value in the 23-gauge phacovitrectomy group was significantly greater than that in the cataract surgery group 24 months after surgery (Po0.05). The rate of capsulotomy in the 20-gauge phacovitrectomy group was significantly higher than that in the cataract surgery group (P ¼ 0.007), whereas there was no significant difference between the 23-gauge phacovitrectomy group and the cataract surgery group. Conclusion PCO rate in eyes with the 23-gauge phacovitrectomy was lower than in those with the 20-gauge phacovitrectomy, and PCO rate even in the 23-gauge phacovitrectomy was higher than in those with cataract surgery.

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“…It is also believed that sharp-edged IOLs and capsular rings can produce a "barrier effect" preventing the migration of these cells and, consequently, the PCO formation (APPLE et al, 2001;KUGELBERG et al, 2008;KOHNEN et al, 2008). Histopathology studies showed that a sharp capsular bend was formed at the sharp posterior optic edge of the IOLs and that the migration of lens was inhibited at this site.…”

Section: Discussionmentioning

confidence: 99%

“…The theory that the shape of the square edge is more important than the IOL materials has gained popularity and the IOLs have been modified in an attempt to effectively reduce PCO formation. Some studies have reported that a sharp posterior optic edge is the main factor in preventing PCO (KOHNEN et al, 2008) due to the "barrier effect" against lens epithelial migration (APPLE et al, 2001). …”

Section: Introductionmentioning

confidence: 99%

Anel de tensão capsular isolado e associado à lente intraocular acrílica dobrável na opacidade de cápsula posterior após facoemulsificação em cães

et al. 2015

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Optic Edge Design as Long-term Factor for Posterior Capsular Opacification Rates

Cited by 89 publications

References 51 publications

Incidence and associated factors of posterior capsule opacification in pseudophakic patients at Cipto Mangunkusumo Hospital

Incidence and associated factors of posterior capsule opacification in pseudophakic patients at Cipto Mangunkusumo Hospital

Posterior capsule opacification following 20- and 23-gauge phacovitrectomy (posterior capsule opacification following phacovitrectomy)

Anel de tensão capsular isolado e associado à lente intraocular acrílica dobrável na opacidade de cápsula posterior após facoemulsificação em cães

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