Optic disc pit: a review

Georgalas, Ilias; Ladas, Ioannis; Georgopoulos, G.; Petrou, Petros

doi:10.1007/s00417-011-1698-5

Cited by 174 publications

(259 citation statements)

References 80 publications

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“…However, development of macular hole causing permanent visual loss, foveolar cystic changes and degenerative retinal pigment epithelial changes can be observed during the resolution period in this group of patients. 2,4,7,10,12,33,34 The poor final visual outcome in the natural course of spontaneously resolved maculopathy may lead to a surgical approach being the preferred modality of treatment at the time of diagnosis. Therefore, we also opted to offer surgical treatment to all patients after diagnosis of ODP maculopathy.…”

Section: Discussionmentioning

confidence: 99%

“…1,2 Congenital optic disc pits (ODP) are bilateral in 10-15% of patients. Serous macular detachment associated with ODP develops within the second to fourth decades of life in 25-75% of cases.…”

Section: Introductionmentioning

confidence: 99%

“…This situation is observed not only due to serous macular detachment but also due to separation within the inner layers of the retina. [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19] Treatment of ODP associated maculopathy is somewhat controversial because there is no consensus regarding the indications for surgical intervention, or the methods and techniques of surgery. Although there are several treatment options for this pathology, none of them has been generally accepted as a choice of treatment method that is shown to be superior to the other treatment methods.…”

Section: Introductionmentioning

confidence: 99%

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Long-term outcomes of pars plana vitrectomy without internal limiting membrane peeling for optic disc pit maculopathy

Avcı

Yılmaz

İnan

et al. 2013

Eye

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Purpose To evaluate the results of surgical treatment of maculopathy secondary to congenital optic pit anomaly with pars plana vitrectomy (PPV), endolaser to the temporal edge of the optic disc and C3F8 tamponade without internal limiting membrane (ILM) peeling. Patients and methods Thirteen eyes of 12 patients with serous macular detachment and/or macular retinoschisis secondary to congenital optic disc pit (ODP) were included in the study. All eyes underwent PPV, posterior hyaloid removal, endolaser photocoagulation on the temporal margin of the optic disc and 12% C3F8 gas tamponade. Anatomic success and functional outcome determined retrospectively by optical coherence tomography and measurement of best corrected visual acuity (BCVA), respectively were the main outcome parameters. Results Two lines or more improvement in BCVA was obtained in 11 eyes and 6 of these eyes had 20/40 or better BCVA at the final visit. Subretinal or intraretinal fluid was completely resorbed postoperatively in 12 eyes but a little intraretinal fluid persisted in one eye at the 16-month follow-up. Better visual improvement was observed in patients treated by earlier surgical intervention. Conclusion PPV, C3F8 gas tamponade and endolaser to the optic disc margin without ILM peeling may yield favourable results in the treatment of ODP maculopathy.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Long-term outcomes of pars plana vitrectomy without internal limiting membrane peeling for optic disc pit maculopathy

Avcı

Yılmaz

İnan

et al. 2013

Eye

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“…1980; Georgalas et al. 2011). Clinically, the condition can be asymptomatic, but a decrease in VA can arise from cystoid macular oedema, retinoschisis (RS) or a serous detachment of the retina (Gass 1969; Lincoff et al.…”

Section: Introductionmentioning

confidence: 99%

Levels of beta‐trace protein in optic disc pit with macular detachment

Makdoumi

Nilsson

Crafoord

2017

Acta Ophthalmologica

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BackgroundTo report beta‐trace protein (β TP) levels in the subretinal fluid (SRF) of four patients with a macular detachment associated with optic disc pit (ODP).MethodsFour patients with a serous retinal detachment involving the macula was operated by pars plana vitrectomy (PPV) with C2F6 gas tamponade and peeling of internal limiting membrane (ILM). Patients with a follow‐up period exceeding one year postoperatively were included in the study. The SRF was drained using a fine cannula without laser photocoagulation, and the samples were analysed using particle‐enhancing nephelometry. The levels of β TP were compared to 20 routine cerebrospinal fluid (CSF) samples.ResultsIn four of the five samples from SRF had relatively low β TP levels, with a mean concentration of 6.6 mg/l (range 2.0 to 23.1 mg/l) compared to 16.0 mg/l (range 6.3‐26.8 mg/l) in CSF. The only SRF sample within the range corresponding to normal CSF was the first sample from patient 4, and the analysis of the renewed aspirate during the second operation was 2.8 mg/l. Postoperatively, the regression of SRF was slow, but regression of SRF in the foveal region took place in all cases; however, visual acuity (VA) was improved in only half of the patients.ConclusionThe results from the analysed SRF regarding β TP concentration in these patients indicate that the SRF in ODP is not identical to CSF, as the concentrations of β TP differ.

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“…1,2 It's a rare clinical entity having an incidence of about 1 in 10,000, being bilateral in only 15% of the cases. 2 It can be either congenital or acquired. Patients with optic disc pits may be asymptomatic, being detected during routine examinations.…”

Section: Introductionmentioning

confidence: 99%