Opsoclonus-Myoclonus-Ataxia Syndrome Due to Covid-19

Abstract

Opsoclonus myoclonus syndrome (OMS) is a rare neurological encephalopathic entity associated with non-speci c infections or cancer processes that has been occasionally described in the setting of SARS-CoV-2 infection. We report a case of a 53-year-old man with SARS-CoV-2 infection, who developed clinical features of opsoclonus-myoclonus syndrome. Of particular note, cerebrospinal uid analysis (CSF) analysis revealed the production of myelin oligodendrocyte glycoprotein (MOG) antibodies, suggesting an underlying neuroimmunological mechanism associated with infection with the novel SARS-CoV-2 virus. Full TextIn addition to the primary medical and epidemiological challenges, the SARS-CoV-2 pandemic has triggered a vivid research activity on the organic dysfunctions associated with the virus known as Covid-19 and numerous investigations have been undertaken aiming to capture and re ne the pathogenetic